Antimicrobial Prophylaxis after Tick Bites

John Genter, Nancy G. Berman, Roberta E. Madison, David A. Drachman, David Magid, Brian S. Schwartz, Joseph Craft, J. Sanford Schwartz, Kenneth B. Liegner, Eugene D. Shapiro, Anne T. Berg, Michael A. Gerber, Henry M. Feder

Research output: Contribution to journalLetterpeer-review

Abstract

To the Editor: We believe Shapiro et al. (Dec. 17 issue)1 had inadequate evidence to support their recommendation for nontreatment of deer-tick bites. The population samples were much too small for a meaningful comparison of the risks of serious late sequelae with the risks and benefits of prophylactic antibiotic therapy. Consider the hypothetical situation of 10,000 deer-tick bites in Connecticut, in which 120 people would acquire the disease and 15 to 36 would not manifest erythema migrans. Magid et al.2 estimate that 60 percent of these people would acquire chronic arthritis, 17 percent meningoencephalitis or neuropathy, and 6 percent cardiac…

Original languageEnglish (US)
Pages (from-to)1418-1420
Number of pages3
JournalNew England Journal of Medicine
Volume328
Issue number19
DOIs
StatePublished - May 13 1993

ASJC Scopus subject areas

  • Medicine(all)

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