Antigenic changes in transformed FL human amnion cells

G. D. Vladutiu, N. R. Rose

Research output: Contribution to journalArticle

Abstract

An FL human amnion cell line, which has long been established as a continuous culture, underwent a spontaneous, 'malignant' transformation. The transformation was associated with the loss of a primate specific esterase isoenzyme, using both antigenic and enzymatic criteria. At the same time, a new, electrophoretically and antigenically distinct esterase was detected in the cell culture.

Original languageEnglish (US)
Pages (from-to)417-426
Number of pages10
JournalClinical and Experimental Immunology
Volume15
Issue number3
StatePublished - Dec 1 1973

ASJC Scopus subject areas

  • Immunology and Allergy
  • Immunology

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