Anticryptococcal type D antibodies raised in rabbits

A. K. Bhattacharjee; J. E. Bennett; D. R. Bundle; C. P.J. Glaudemans

doi:10.1016/0161-5890(83)90016-0

Anticryptococcal type D antibodies raised in rabbits

A. K. Bhattacharjee, J. E. Bennett, D. R. Bundle, C. P.J. Glaudemans

School of Medicine

Research output: Contribution to journal › Article › peer-review

6 Scopus citations

Abstract

Antibodies to Cryptococcus neoformans Type D have been raised in rabbits. The partially purified antibody pool was fractionated by affinity-chromatography, and it was shown that antibodies to the capsular polysaccharide of Type D were present in the pool. Neither methyl α-d-mannopyranoside, nor d-mannose were inhibitors of the binding of Type D polysaccharide to the antibody-pool. Thus it appears that the serum contains antibody populations which are specific for terminal side-chain carbohydrate moieties of the immunizing antigen.

Original language	English (US)
Pages (from-to)	351-359
Number of pages	9
Journal	Molecular Immunology
Volume	20
Issue number	4
DOIs	https://doi.org/10.1016/0161-5890(83)90016-0
State	Published - Apr 1983

ASJC Scopus subject areas

Immunology
Molecular Biology

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abstract = "Antibodies to Cryptococcus neoformans Type D have been raised in rabbits. The partially purified antibody pool was fractionated by affinity-chromatography, and it was shown that antibodies to the capsular polysaccharide of Type D were present in the pool. Neither methyl α-d-mannopyranoside, nor d-mannose were inhibitors of the binding of Type D polysaccharide to the antibody-pool. Thus it appears that the serum contains antibody populations which are specific for terminal side-chain carbohydrate moieties of the immunizing antigen.",

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AU - Bhattacharjee, A. K.

AU - Bennett, J. E.

AU - Bundle, D. R.

AU - Glaudemans, C. P.J.

PY - 1983/4

Y1 - 1983/4

N2 - Antibodies to Cryptococcus neoformans Type D have been raised in rabbits. The partially purified antibody pool was fractionated by affinity-chromatography, and it was shown that antibodies to the capsular polysaccharide of Type D were present in the pool. Neither methyl α-d-mannopyranoside, nor d-mannose were inhibitors of the binding of Type D polysaccharide to the antibody-pool. Thus it appears that the serum contains antibody populations which are specific for terminal side-chain carbohydrate moieties of the immunizing antigen.

AB - Antibodies to Cryptococcus neoformans Type D have been raised in rabbits. The partially purified antibody pool was fractionated by affinity-chromatography, and it was shown that antibodies to the capsular polysaccharide of Type D were present in the pool. Neither methyl α-d-mannopyranoside, nor d-mannose were inhibitors of the binding of Type D polysaccharide to the antibody-pool. Thus it appears that the serum contains antibody populations which are specific for terminal side-chain carbohydrate moieties of the immunizing antigen.

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Anticryptococcal type D antibodies raised in rabbits

Abstract

ASJC Scopus subject areas

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