Anticryptococcal type D antibodies raised in rabbits

A. K. Bhattacharjee, J. E. Bennett, D. R. Bundle, C. P.J. Glaudemans

Research output: Contribution to journalArticlepeer-review

Abstract

Antibodies to Cryptococcus neoformans Type D have been raised in rabbits. The partially purified antibody pool was fractionated by affinity-chromatography, and it was shown that antibodies to the capsular polysaccharide of Type D were present in the pool. Neither methyl α-d-mannopyranoside, nor d-mannose were inhibitors of the binding of Type D polysaccharide to the antibody-pool. Thus it appears that the serum contains antibody populations which are specific for terminal side-chain carbohydrate moieties of the immunizing antigen.

Original languageEnglish (US)
Pages (from-to)351-359
Number of pages9
JournalMolecular Immunology
Volume20
Issue number4
DOIs
StatePublished - Apr 1983

ASJC Scopus subject areas

  • Immunology
  • Molecular Biology

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