Anticoagulation Therapy in Microsurgery: A Review

Morad Askari, Christine Fisher, Frederick G. Weniger, Sean Bidic, W P Andrew Lee

Research output: Contribution to journalArticle

Abstract

The advent of microsurgical tissue transfer including replantation greatly has expanded the scope of reconstructive surgery. There are few recent innovations in anticoagulation therapies for microsurgery, however, and anastomotic thrombosis remains an occasional cause of surgical failure. No consensus exists on the ideal anticoagulation protocol for microsurgery. This article reviews major pharmacologic modalities of anticoagulation, delineates the mechanism of action and study of efficacy of each agent, and compares the risks and benefits of popular anticoagulation therapies. Finally, it examines available human outcomes-based data and attempts to provide a glimpse of the future direction of microsurgical anticoagulation research.

Original languageEnglish (US)
Pages (from-to)836-846
Number of pages11
JournalJournal of Hand Surgery
Volume31
Issue number5
DOIs
StatePublished - May 2006
Externally publishedYes

Fingerprint

Microsurgery
Reconstructive Surgical Procedures
Replantation
Thrombosis
Therapeutics
Research
Direction compound

Keywords

  • anticoagulation
  • flap
  • heparin
  • Microsurgery
  • thrombosis

ASJC Scopus subject areas

  • Orthopedics and Sports Medicine
  • Surgery

Cite this

Askari, M., Fisher, C., Weniger, F. G., Bidic, S., & Lee, W. P. A. (2006). Anticoagulation Therapy in Microsurgery: A Review. Journal of Hand Surgery, 31(5), 836-846. https://doi.org/10.1016/j.jhsa.2006.02.023

Anticoagulation Therapy in Microsurgery : A Review. / Askari, Morad; Fisher, Christine; Weniger, Frederick G.; Bidic, Sean; Lee, W P Andrew.

In: Journal of Hand Surgery, Vol. 31, No. 5, 05.2006, p. 836-846.

Research output: Contribution to journalArticle

Askari, M, Fisher, C, Weniger, FG, Bidic, S & Lee, WPA 2006, 'Anticoagulation Therapy in Microsurgery: A Review', Journal of Hand Surgery, vol. 31, no. 5, pp. 836-846. https://doi.org/10.1016/j.jhsa.2006.02.023
Askari M, Fisher C, Weniger FG, Bidic S, Lee WPA. Anticoagulation Therapy in Microsurgery: A Review. Journal of Hand Surgery. 2006 May;31(5):836-846. https://doi.org/10.1016/j.jhsa.2006.02.023
Askari, Morad ; Fisher, Christine ; Weniger, Frederick G. ; Bidic, Sean ; Lee, W P Andrew. / Anticoagulation Therapy in Microsurgery : A Review. In: Journal of Hand Surgery. 2006 ; Vol. 31, No. 5. pp. 836-846.
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