TY - JOUR
T1 - Antibody Testing in Lyme Disease A Comparison of Results in Four Laboratories
AU - Schwartz, Brian S.
AU - Goldstein, Michael D.
AU - Ribeiro, Jose M.C.
AU - Schulze, Terry L.
AU - Shahied, S. I.
PY - 1989/12/22
Y1 - 1989/12/22
N2 - To evaluate the interlaboratory and intralaboratory agreement in the performance of Lyme disease serological testing, we sent serum specimens from 132 outdoor workers in New Jersey to as many as four independent laboratories. These included one state department of health laboratory, one large commercial laboratory, and two research laboratories. The measurement of agreement employed, the kappa statistic, ranged from.45 to.53 among the four laboratories and from.50 to.54 within the commercial laboratory. These values represent low levels of agreement. The data suggest that Lyme disease serological testing procedures should be standardized so that Lyme disease test results are more comparable between laboratories.
AB - To evaluate the interlaboratory and intralaboratory agreement in the performance of Lyme disease serological testing, we sent serum specimens from 132 outdoor workers in New Jersey to as many as four independent laboratories. These included one state department of health laboratory, one large commercial laboratory, and two research laboratories. The measurement of agreement employed, the kappa statistic, ranged from.45 to.53 among the four laboratories and from.50 to.54 within the commercial laboratory. These values represent low levels of agreement. The data suggest that Lyme disease serological testing procedures should be standardized so that Lyme disease test results are more comparable between laboratories.
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U2 - 10.1001/jama.1989.03430240067031
DO - 10.1001/jama.1989.03430240067031
M3 - Article
C2 - 2685383
AN - SCOPUS:0024784610
SN - 0098-7484
VL - 262
SP - 3431
EP - 3434
JO - JAMA: The Journal of the American Medical Association
JF - JAMA: The Journal of the American Medical Association
IS - 24
ER -