Antibody-mediated red blood cell agglutination resulting in spontaneous echocardiographic contrast

Research output: Contribution to journalArticle


Spontaneous echocardiographic contrast is well reported in states of low flow and low shear stress, and the primary blood component involved has been reported as red blood cells via rouleaux formation. This report describes the occurrence of spontaneous echocardiographic contrast from a unique mechanism of IgM-mediated red blood cell agglutination and describes the clinical sequelae.

Original languageEnglish (US)
Pages (from-to)287-289
Number of pages3
JournalPediatric Cardiology
Issue number4
StatePublished - Jul 1999



  • Autoimmune hemolytic anemia
  • Spontaneous contrast
  • Warm-reacting IgM antibody

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine
  • Pediatrics, Perinatology, and Child Health

Cite this