Abstract
Murine cryptocococcal pulmonary infection elicited serum immunoglobulin M (IgM) and IgG to the capsular polysaccharide, but only IgG stained yeast cells in alveoli. Both isotypes produced punctuate immunofluorescence patterns on yeast cells like those of nonprotective antibodies. The difficulties involved in associating humoral immunity with protection in murine cryptocococcal infection could reflect nonprotective antibody responses.
Original language | English (US) |
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Pages (from-to) | 4271-4274 |
Number of pages | 4 |
Journal | Infection and immunity |
Volume | 72 |
Issue number | 7 |
DOIs | |
State | Published - Jul 2004 |
Externally published | Yes |
ASJC Scopus subject areas
- Parasitology
- Microbiology
- Immunology
- Infectious Diseases