Antibiotic-loaded articulating cement spacer in the 2-stage exchange of infected total knee arthroplasty

Sridhar M. Durbhakula, John Czajka, Marc D. Fuchs, Richard L. Uhl

Research output: Contribution to journalArticlepeer-review

115 Scopus citations


An antibiotic-loaded articulating cement spacer (ALACS) was used in the 2-stage exchange of infected total knee arthroplasty. Specially designed molds produced articulating femoral and tibial spacer components. Twenty-four consecutive patients were followed for an average of 33 months (range, 28-51 months). Two patients (8%) had a persistent infection after the first stage. Twenty-two patients (92%) underwent a successful 2-stage exchange. Minimal soft-tissue contracture and minimal bone loss were encountered during reimplantation. None of these patients developed a recurrent or persistent infection. The average postoperative knee flexion was 104°(range, 89°-122°). The average Hospital for Special Surgery score was 82 (range, 63-96). The ALACS spacer preserved knee function between stages, resulting in effective treatment of infection, facilitation of reimplantation, and improved patient satisfaction.

Original languageEnglish (US)
Pages (from-to)768-774
Number of pages7
JournalJournal of Arthroplasty
Issue number6
StatePublished - Sep 2004


  • 2-stage exchange
  • articulating spacer
  • infection
  • total knee arthroplasty

ASJC Scopus subject areas

  • Orthopedics and Sports Medicine


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