Anti-/propsychotic drug signaling via heteromeric GPCRs-A balancing act?

Mari Kondo, Akira Sawa

Research output: Contribution to journalShort survey

Abstract

In this issue, Fribourg et al. provide insight into a molecular basis of psychosis. They reveal that a heteromeric complex formed by the G protein-coupled receptors (GPCRs) for glutamate and serotonin is a convergent site for the activity of anti-or propsychotic drugs, opening a possibility for new therapeutic strategies for schizophrenia.

Original languageEnglish (US)
Pages (from-to)964-965
Number of pages2
JournalCell
Volume147
Issue number5
DOIs
StatePublished - Nov 23 2011

ASJC Scopus subject areas

  • Biochemistry, Genetics and Molecular Biology(all)

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