Anti histone KSAchicken antibody from guinea pig

C. Mura, P. C. Huang, D. A. Levy

Research output: Contribution to journalArticlepeer-review

13 Scopus citations

Abstract

Avian erythrocyte-specific histone KSA was purified from chicken red blood cells by selective extraction and by chromatography on amberlite CG-50 columns. This histone was used in the production of antibody in guinea pigs. By immunoprecipitation and microcomplement-fixation tests, the antibody was shown to be specific for histone KSA; reaction was not seen with histones KAP, ARE, GRK, LAK, and KAS. The observation supports the notion that histone KSA has an independent origin from that of other histones.

Original languageEnglish (US)
Pages (from-to)750-755
Number of pages6
JournalJournal of Immunology
Volume113
Issue number3
StatePublished - Dec 1 1974

ASJC Scopus subject areas

  • Immunology and Allergy
  • Immunology

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