Four phenolic amides, dihydro-N-caffeoyltyramine (1), trans-N- feruloyloctopamine (2), trans-N-caffeoyltyramine (3), and cis-N-caffeoyltyramine (4), were isolated from an ethyl acetate extract of the root bark of Lycium chinense Miller. All had an anti-fungal effect; compounds 1-3 were potent at 5-10 μg ml -1 and were without hemolytic activity against human erythrocyte cells. Compound 4 was active at 40 μg ml -1. All four compounds impeded the dimorphic transition of pathogen, Candida albicans.
|Original language||English (US)|
|Number of pages||6|
|State||Published - Jul 2004|
- Lycium chinense
- anti-fungal activity
ASJC Scopus subject areas
- Applied Microbiology and Biotechnology