Anthropometric Measures at Multiple Times Throughout Life and Prostate Cancer Diagnosis, Metastasis, and Death

Axel Gerdtsson, Jessica B. Poon, Daniel L. Thorek, Lorelei A. Mucci, Michael J. Evans, Peter Scardino, Per Anders Abrahamsson, Peter Nilsson, Jonas Manjer, Anders Bjartell, Johan Malm, Andrew Vickers, Stephen J. Freedland, Hans Lilja, David Ulmert

Research output: Contribution to journalArticle

Abstract

Background Previous studies of prostate cancer (PCA) risk and anthropometrics (ie, body measurements) were based on single measurements or obtained over limited time spans. Objective To study the association between anthropometrics measured at multiple time points in life and their relation to later diagnosis, metastasis, or death from PCA. Design, setting, and participants This case-control study includes 27 167 Swedish men enrolled in two population-based projects from 1974 to 1996. PCA diagnosis up to December 31, 2006, disease information, gestation time, and anthropometrics at birth, military conscript testing, and adulthood were collected. A total of 1355 PCA cases were matched with 5271 controls. Outcome measurements and statistical analysis Univariate conditional logistic regression was used to determine whether clinical diagnosis, metastasis, or PCA death was associated with low birth weight (weight

Original languageEnglish (US)
Pages (from-to)1076-1082
Number of pages7
JournalEuropean Urology
Volume68
Issue number6
DOIs
StatePublished - 2015

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Keywords

  • Exposure windows
  • Long-term risk predictions
  • Metabolic syndrome-associated anthropometrics
  • Prostate cancer
  • Risk factors

ASJC Scopus subject areas

  • Urology

Cite this

Gerdtsson, A., Poon, J. B., Thorek, D. L., Mucci, L. A., Evans, M. J., Scardino, P., Abrahamsson, P. A., Nilsson, P., Manjer, J., Bjartell, A., Malm, J., Vickers, A., Freedland, S. J., Lilja, H., & Ulmert, D. (2015). Anthropometric Measures at Multiple Times Throughout Life and Prostate Cancer Diagnosis, Metastasis, and Death. European Urology, 68(6), 1076-1082. https://doi.org/10.1016/j.eururo.2015.03.017