Anterior temporal language areas in patients with early onset of temporal lobe epilepsy

Orrin Devinsky, Kenneth Perrine, Rafael H Llinas, Daniel J. Luciano, Michael Dogali

Research output: Contribution to journalArticle

Abstract

Eighteen consecutive patients undergoing dominant temporal lobectomy underwent preoperative cortical stimulation for language localization. Patients with naming deficits on anterior (4.5 cm from the temporal pole) temporal lobe stimulation had earlier seizure onset vs those without such deficits (5.8 yr vs 12.9 yr; p <0.04). There was a similar trend for reading errors (6.3 yr vs 12.4 yr; p <0.052). Resections always spared at least 1 cm anterior to any langauge area. There was no significant difference in postoperative neuropsychological tests between patients with and without anterior language representation. Early onset of dominant temporal lobe seizure foci leads to a more widespread or atypical distribution of language areas. Individual variability should be considered in epilepsy surgery to reduce postoperative language deficits.

Original languageEnglish (US)
Pages (from-to)727-732
Number of pages6
JournalAnnals of Neurology
Volume34
Issue number5
StatePublished - Nov 1993
Externally publishedYes

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Temporal Lobe Epilepsy
Language
Temporal Lobe
Seizures
Neuropsychological Tests
Reading
Epilepsy

ASJC Scopus subject areas

  • Neuroscience(all)

Cite this

Devinsky, O., Perrine, K., Llinas, R. H., Luciano, D. J., & Dogali, M. (1993). Anterior temporal language areas in patients with early onset of temporal lobe epilepsy. Annals of Neurology, 34(5), 727-732.

Anterior temporal language areas in patients with early onset of temporal lobe epilepsy. / Devinsky, Orrin; Perrine, Kenneth; Llinas, Rafael H; Luciano, Daniel J.; Dogali, Michael.

In: Annals of Neurology, Vol. 34, No. 5, 11.1993, p. 727-732.

Research output: Contribution to journalArticle

Devinsky, O, Perrine, K, Llinas, RH, Luciano, DJ & Dogali, M 1993, 'Anterior temporal language areas in patients with early onset of temporal lobe epilepsy', Annals of Neurology, vol. 34, no. 5, pp. 727-732.
Devinsky, Orrin ; Perrine, Kenneth ; Llinas, Rafael H ; Luciano, Daniel J. ; Dogali, Michael. / Anterior temporal language areas in patients with early onset of temporal lobe epilepsy. In: Annals of Neurology. 1993 ; Vol. 34, No. 5. pp. 727-732.
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