Antagonistic behavior, dominance, hostility, and coronary heart disease

Aron Wolfe Siegman, Susan T. Townsend, A. Cahid Civelek, Roger S. Blumenthal

Research output: Contribution to journalArticlepeer-review


Purpose: This study investigated the relationship between antagonistic behavior, dominance, attitudinal, hostility, and coronary heart disease (CHD). Methods: One hundred one men and 95 women referred for thallium stress testing were administered the Structured Interview and the Cook-Medley Hostility Scale. The Hostile. Behavior Index, derived from the Structured Interview and developed by Haney et al., served as an index of antagonism, and the frequency with which interviewees interrupted their interviewer served as a measure of dominance. On the basis of their medical history and thallium stress test results, patients were classified as having (N = 44) or not having (N = 99) CHD. Results and Conclusions: Multivariate logistic regressions (with age, gender, disease, and lifestyle risk factors in the model) revealed that both the Hostile Behavior Index and dominance were significant independent risk factors for CHD (relative risk [RR] = 1.22 and 1.47, p < .03). Of the two Hostile Behavior Index component scores, indirect challenge and irritability, only the latter correlated significantly with CHD (RR = 1.27, p < .03). Separate logistic regressions for men and women suggest that subtle, indirect manifestations of antagonism confer CHD risk in women and that more overt expressions of anger confer risk in men. A significant univariate correlation between hostility scale scores and CHD became not significant when we adjusted for socioeconomic status.

Original languageEnglish (US)
Pages (from-to)248-257
Number of pages10
JournalPsychosomatic medicine
Issue number2
StatePublished - 2000
Externally publishedYes


  • Antagonism
  • Coronary heart disease
  • Dominance
  • Hostility
  • Irritability
  • Socioeconomic status

ASJC Scopus subject areas

  • Applied Psychology
  • Psychiatry and Mental health


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