Ankylosing spondylitis with selective IgA deficiency and a circulating anticoagulant.

A. E. Good, J. T. Cassidy, M. G. Mutchnick, R. E. Reed, H. M. Lederman

Research output: Contribution to journalArticle

Abstract

A patient with ankylosing spondylitis was found to have selective IgA deficiency and a non-heparin, immediate-acting antithrombin (antithrombin V). T cells were decreased, and serum IgG was increased. In vitro synthesis of IgG by peripheral blood lymphocytes was very high. This association of ankylosing spondylitis with the T cell and protein abnormalities is probably fortuitous but does demonstrate that severe spondylitis may evolve in the absence of IgA.

Original languageEnglish (US)
Pages (from-to)297-302
Number of pages6
JournalJournal of Rheumatology
Volume4
Issue number3
StatePublished - Sep 1 1977
Externally publishedYes

ASJC Scopus subject areas

  • Rheumatology
  • Immunology and Allergy
  • Immunology

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  • Cite this

    Good, A. E., Cassidy, J. T., Mutchnick, M. G., Reed, R. E., & Lederman, H. M. (1977). Ankylosing spondylitis with selective IgA deficiency and a circulating anticoagulant. Journal of Rheumatology, 4(3), 297-302.