A patient with ankylosing spondylitis was found to have selective IgA deficiency and a non-heparin, immediate-acting antithrombin (antithrombin V). T cells were decreased, and serum IgG was increased. In vitro synthesis of IgG by peripheral blood lymphocytes was very high. This association of ankylosing spondylitis with the T cell and protein abnormalities is probably fortuitous but does demonstrate that severe spondylitis may evolve in the absence of IgA.
|Original language||English (US)|
|Number of pages||6|
|Journal||Journal of Rheumatology|
|State||Published - Sep 1 1977|
ASJC Scopus subject areas
- Immunology and Allergy