Ankylosing spondylitis and axial spondyloarthritis

Joel D. Taurog, Avneesh Chhabra, Robert A. Colbert

Research output: Contribution to journalReview article

Abstract

Chronic back pain is common worldwide and is cared for by a variety of providers, but specific, satisfactory treatment is often lacking. Ankylosing spondylitis, an inflammatory disorder that in its extreme form can lead to the bony fusion of vertebral joints, is an uncommon but well-established cause of chronic back pain. During the past decade, ankylosing spondylitis has come to be considered as a subset of the broader and more prevalent diagnostic entity referred to as axial spondyloarthritis. The estimated prevalence of axial spondyloarthritis in the United States is 0.9 to 1.4% of the adult population, similar to that of rheumatoid arthritis.1 Axial spondyloarthritis is generally diagnosed and treated by rheumatologists, and there is specific treatment for it. However, prolonged delay in reaching the diagnosis is common and is usually the result of the failure of recognition by nonrheumatologists.2 This review is intended to enhance awareness and understanding of axial spondyloarthritis and ankylosing spondylitis - and the relationship between the two - in order to facilitate prompt and accurate diagnosis and proper treatment. Recent advances in our understanding and treatment of these conditions are discussed.

Original languageEnglish (US)
Pages (from-to)2563-2574
Number of pages12
JournalNew England Journal of Medicine
Volume374
Issue number26
DOIs
StatePublished - Jun 30 2016
Externally publishedYes

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Ankylosing Spondylitis
Back Pain
Chronic Pain
Therapeutics
Joints
Population

ASJC Scopus subject areas

  • Medicine(all)

Cite this

Ankylosing spondylitis and axial spondyloarthritis. / Taurog, Joel D.; Chhabra, Avneesh; Colbert, Robert A.

In: New England Journal of Medicine, Vol. 374, No. 26, 30.06.2016, p. 2563-2574.

Research output: Contribution to journalReview article

Taurog, JD, Chhabra, A & Colbert, RA 2016, 'Ankylosing spondylitis and axial spondyloarthritis', New England Journal of Medicine, vol. 374, no. 26, pp. 2563-2574. https://doi.org/10.1056/NEJMra1406182
Taurog, Joel D. ; Chhabra, Avneesh ; Colbert, Robert A. / Ankylosing spondylitis and axial spondyloarthritis. In: New England Journal of Medicine. 2016 ; Vol. 374, No. 26. pp. 2563-2574.
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