Animal models for the study of maturity-onset and hereditary cataract

J. Samuel Zigler

Research output: Contribution to journalArticlepeer-review

Abstract

The increasing use of animal models in the study of cataract has been one of the most important trends in lens research over the last two decades. The number of animal models available for both hereditary congenital cataracts and for maturity-onset cataracts has grown substantially during this time. Analysis of some of these systems by biochemical and molecular biology techniques has resulted in significant and often surprising insights into the basic biology of the lens, as well as the process of cataractogenesis. The following is a brief overview of those animal models for which biochemical studies have been reported.

Original languageEnglish (US)
Pages (from-to)651-657
Number of pages7
JournalExperimental eye research
Volume50
Issue number6
DOIs
StatePublished - Jun 1990

Keywords

  • animal models
  • cataract
  • hereditary cataract
  • maturity-onset cataract

ASJC Scopus subject areas

  • Ophthalmology
  • Sensory Systems
  • Cellular and Molecular Neuroscience

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