@article{5ce3ed12957e439fa5f41dffa535b652,
title = "Anhydrous nanoprecipitation for the preparation of nanodispersions of tenofovir disoproxil fumarate in oils as candidate long-acting injectable depot formulations",
abstract = "The facile formation of drug nanoparticles in injectable/ingestible oils, of water-soluble antiretroviral tenofovir disoproxil fumarate, using a novel nanoprecipitation is presented with studies showing drug release into relevant aqueous media.",
author = "Hobson, {James J.} and Paul Curley and Savage, {Alison C.} and Amer Al-Khouja and Marco Siccardi and Charles Flexner and Meyers, {Caren Freel} and Andrew Owen and Rannard, {Steve P.}",
note = "Funding Information: The authors are inventors on patents that seek to protect TDF nanoprecipitation to allow charitable access. C. F. reports serving as a paid consultant for Cipla Pharmaceuticals, Janssen Pharmaceuticals, Merck Laboratories, Mylan Pharmaceuticals, and ViiV Healthcare, and received research grant support from Gilead Sciences paid to his University. AO and SR are directors of Tandem Nano Ltd. AO and SR have received research funding from ViiV Healthcare and AstraZeneca; AO has acted as a personal consultant to Gilead, ViiV Healthcare and Merck. The authors declare no competing interests. Funding Information: The authors are grateful for funding from the US National Institutes of Health (NIH) under grant number R01AI114405-01 and a Ruth L. Kirschstein National Research Service Award (NRSA) pre-doctoral fellowship from the NIH (F31 AI129549, awarded to A. A.-k.). The authors also wish to acknowledge the Centre for Materials Discovery at the University of Liverpool for access to analytical equipment. Publisher Copyright: {\textcopyright} 2019 The Royal Society of Chemistry.",
year = "2019",
doi = "10.1039/c9na00529c",
language = "English (US)",
volume = "1",
pages = "4301--4307",
journal = "Nanoscale Advances",
issn = "2516-0230",
publisher = "Royal Society of Chemistry",
number = "11",
}