Angioinvasive, cutaneous infection due to Colletotrichum siamense in a stem cell transplant recipient: Report and review of prior cases

William A. Werbel; Riccardo Baroncelli; Shmuel Shoham; Sean X. Zhang

doi:10.1111/tid.13153

Angioinvasive, cutaneous infection due to Colletotrichum siamense in a stem cell transplant recipient: Report and review of prior cases

William A. Werbel, Riccardo Baroncelli, Shmuel Shoham, Sean X. Zhang

School of Medicine

Research output: Contribution to journal › Article › peer-review

1 Scopus citations

Abstract

Colletotrichum is an important fungal plant pathogen, yet an uncommon cause of human disease. Herein we report a case of invasive, cutaneous infection in a stem cell transplant recipient due to Colletotrichum species, with accompanying review of the literature. The infection was successfully treated with a combination of liposomal amphotericin B and voriconazole. Multilocus phylogenetic analysis revealed that the distinct isolate belongs to Colletotrichum siamense, a member of the Colletotrichum gloeosporioides species complex not previously described as a human pathogen. Colletotrichum infection remains in the differential for skin lesions in the immune compromised host.

Original language	English (US)
Article number	e13153
Journal	Transplant Infectious Disease
Volume	21
Issue number	5
DOIs	https://doi.org/10.1111/tid.13153
State	Published - Oct 1 2019

Keywords

Colletotrichum
Colletotrichum gloeosporioides
Colletotrichum siamense
Glomerella
phaeohyphomycosis
stem cell transplant

ASJC Scopus subject areas

Transplantation
Infectious Diseases

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10.1111/tid.13153

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title = "Angioinvasive, cutaneous infection due to Colletotrichum siamense in a stem cell transplant recipient: Report and review of prior cases",

abstract = "Colletotrichum is an important fungal plant pathogen, yet an uncommon cause of human disease. Herein we report a case of invasive, cutaneous infection in a stem cell transplant recipient due to Colletotrichum species, with accompanying review of the literature. The infection was successfully treated with a combination of liposomal amphotericin B and voriconazole. Multilocus phylogenetic analysis revealed that the distinct isolate belongs to Colletotrichum siamense, a member of the Colletotrichum gloeosporioides species complex not previously described as a human pathogen. Colletotrichum infection remains in the differential for skin lesions in the immune compromised host.",

keywords = "Colletotrichum, Colletotrichum gloeosporioides, Colletotrichum siamense, Glomerella, phaeohyphomycosis, stem cell transplant",

author = "Werbel, {William A.} and Riccardo Baroncelli and Shmuel Shoham and Zhang, {Sean X.}",

note = "Funding Information: The authors would like to thank the staff members in the Mycology Laboratory at the Johns Hopkins Hospital for their excellent technical support. Publisher Copyright: {\textcopyright} 2019 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd",

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AU - Shoham, Shmuel

AU - Zhang, Sean X.

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AB - Colletotrichum is an important fungal plant pathogen, yet an uncommon cause of human disease. Herein we report a case of invasive, cutaneous infection in a stem cell transplant recipient due to Colletotrichum species, with accompanying review of the literature. The infection was successfully treated with a combination of liposomal amphotericin B and voriconazole. Multilocus phylogenetic analysis revealed that the distinct isolate belongs to Colletotrichum siamense, a member of the Colletotrichum gloeosporioides species complex not previously described as a human pathogen. Colletotrichum infection remains in the differential for skin lesions in the immune compromised host.

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Angioinvasive, cutaneous infection due to Colletotrichum siamense in a stem cell transplant recipient: Report and review of prior cases

Abstract

Keywords

ASJC Scopus subject areas

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