Angiogenesis-related microRNAs in colon cancer

Liu Hong, Yu Han, Yi Zhou, Nita Ahuja

Research output: Contribution to journalArticle

Abstract

Introduction: Angiogenesis, for its fundamental role in cancer growth and metastasis, has become an appealing target in cancer therapy. A number of angiogenesis-related microRNAs (miRNAs) are under investigation and they can affect the cancerous phenotype of malignant cells. Areas covered: The authors review the recent advances in angiogenesis-related miRNAs in human colon cancer. They also envisage future developments toward potential miRNA-based applications to cancer treatment. Expert opinion: Angiogenesis-related miRNAs may reasonably be considered as a valuable cancer therapeutic tool. More investigations should be performed to promote therapeutic-clinical research of miRNAs in patients with colon cancer.

Original languageEnglish (US)
Pages (from-to)77-84
Number of pages8
JournalExpert Opinion on Biological Therapy
Volume13
Issue number1
DOIs
StatePublished - Jan 2013

Fingerprint

MicroRNAs
Colonic Neoplasms
Neoplasms
Therapeutic Human Experimentation
Oncology
Expert Testimony
Therapeutics
Neoplasm Metastasis
Phenotype
Growth

Keywords

  • Angiogenesis
  • Colon cancer
  • MicroRNA
  • MiR-107
  • MiR-145
  • MiR-194
  • MiR-27a
  • MiR-802

ASJC Scopus subject areas

  • Pharmacology
  • Clinical Biochemistry
  • Drug Discovery

Cite this

Angiogenesis-related microRNAs in colon cancer. / Hong, Liu; Han, Yu; Zhou, Yi; Ahuja, Nita.

In: Expert Opinion on Biological Therapy, Vol. 13, No. 1, 01.2013, p. 77-84.

Research output: Contribution to journalArticle

Hong, Liu ; Han, Yu ; Zhou, Yi ; Ahuja, Nita. / Angiogenesis-related microRNAs in colon cancer. In: Expert Opinion on Biological Therapy. 2013 ; Vol. 13, No. 1. pp. 77-84.
@article{158bcaf5f356401f920a905a8c97cf40,
title = "Angiogenesis-related microRNAs in colon cancer",
abstract = "Introduction: Angiogenesis, for its fundamental role in cancer growth and metastasis, has become an appealing target in cancer therapy. A number of angiogenesis-related microRNAs (miRNAs) are under investigation and they can affect the cancerous phenotype of malignant cells. Areas covered: The authors review the recent advances in angiogenesis-related miRNAs in human colon cancer. They also envisage future developments toward potential miRNA-based applications to cancer treatment. Expert opinion: Angiogenesis-related miRNAs may reasonably be considered as a valuable cancer therapeutic tool. More investigations should be performed to promote therapeutic-clinical research of miRNAs in patients with colon cancer.",
keywords = "Angiogenesis, Colon cancer, MicroRNA, MiR-107, MiR-145, MiR-194, MiR-27a, MiR-802",
author = "Liu Hong and Yu Han and Yi Zhou and Nita Ahuja",
year = "2013",
month = "1",
doi = "10.1517/14712598.2013.727391",
language = "English (US)",
volume = "13",
pages = "77--84",
journal = "Expert Opinion on Biological Therapy",
issn = "1471-2598",
publisher = "Informa Healthcare",
number = "1",

}

TY - JOUR

T1 - Angiogenesis-related microRNAs in colon cancer

AU - Hong, Liu

AU - Han, Yu

AU - Zhou, Yi

AU - Ahuja, Nita

PY - 2013/1

Y1 - 2013/1

N2 - Introduction: Angiogenesis, for its fundamental role in cancer growth and metastasis, has become an appealing target in cancer therapy. A number of angiogenesis-related microRNAs (miRNAs) are under investigation and they can affect the cancerous phenotype of malignant cells. Areas covered: The authors review the recent advances in angiogenesis-related miRNAs in human colon cancer. They also envisage future developments toward potential miRNA-based applications to cancer treatment. Expert opinion: Angiogenesis-related miRNAs may reasonably be considered as a valuable cancer therapeutic tool. More investigations should be performed to promote therapeutic-clinical research of miRNAs in patients with colon cancer.

AB - Introduction: Angiogenesis, for its fundamental role in cancer growth and metastasis, has become an appealing target in cancer therapy. A number of angiogenesis-related microRNAs (miRNAs) are under investigation and they can affect the cancerous phenotype of malignant cells. Areas covered: The authors review the recent advances in angiogenesis-related miRNAs in human colon cancer. They also envisage future developments toward potential miRNA-based applications to cancer treatment. Expert opinion: Angiogenesis-related miRNAs may reasonably be considered as a valuable cancer therapeutic tool. More investigations should be performed to promote therapeutic-clinical research of miRNAs in patients with colon cancer.

KW - Angiogenesis

KW - Colon cancer

KW - MicroRNA

KW - MiR-107

KW - MiR-145

KW - MiR-194

KW - MiR-27a

KW - MiR-802

UR - http://www.scopus.com/inward/record.url?scp=84870880747&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84870880747&partnerID=8YFLogxK

U2 - 10.1517/14712598.2013.727391

DO - 10.1517/14712598.2013.727391

M3 - Article

C2 - 23163807

AN - SCOPUS:84870880747

VL - 13

SP - 77

EP - 84

JO - Expert Opinion on Biological Therapy

JF - Expert Opinion on Biological Therapy

SN - 1471-2598

IS - 1

ER -