Anger experiences among hepatitis C patients: Relationship to depressive symptoms and health-related quality of life

Amy A. Dan, Cathy Crone, Thomas N. Wise, Lisa M. Martin, Lolita Ramsey, Scarlett Magee, Robert Sjogren, Janus P. Ong, Zobair M. Younossi

Research output: Contribution to journalArticlepeer-review

Abstract

The authors examined anger among hepatitis C (HCV) patients and its relationship to health-related quality of life (HRQL) and depression. Eighty-seven HCV patients who received pegylated interferon-alpha2b and ribavirin were included. Patients' mean age was 48 years; 42% were women, and 60% were white. Patients experienced moderate anger while undergoing HCV treatment. Angry feelings increased during treatment in some domains, specifically, Control Over Anger and Angry Reaction. Greater anger was associated with more depression and poorer HRQL. Findings point to the importance for physicians to screen for a wide range of neuropsychiatric side effects of interferon, including anger.

Original languageEnglish (US)
Pages (from-to)223-229
Number of pages7
JournalPsychosomatics
Volume48
Issue number3
DOIs
StatePublished - Jan 1 2007
Externally publishedYes

ASJC Scopus subject areas

  • Arts and Humanities (miscellaneous)
  • Applied Psychology
  • Psychiatry and Mental health

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