Anesthetic considerations for the pediatric oncology patient - Part 2: Systems-based approach to anesthesia

Gregory J. Latham, Robert S Greenberg

Research output: Contribution to journalArticle

Abstract

One of the prices paid for chemo- and radiotherapy of cancer in children is damage to the vulnerable and developing healthy tissues of the body. Such damage can exist clinically or subclinically and can become apparent during active antineoplastic treatment or during remission decades later. Furthermore, effects of the tumor itself can significantly impact the physiologic state of the child. The anesthesiologist who cares for children with cancer or for survivors of childhood cancer should understand what effects cancer and its therapy can have on various organ systems. In part two of this three-part review, we review the anesthetic issues associated with childhood cancer. Specifically, this review presents a systems-based approach to the impact from both tumor and its treatment in children, followed by a discussion of the relevant anesthetic considerations.

Original languageEnglish (US)
Pages (from-to)396-420
Number of pages25
JournalPaediatric Anaesthesia
Volume20
Issue number5
DOIs
StatePublished - May 2010

Fingerprint

Anesthetics
Anesthesia
Pediatrics
Neoplasms
Child Care
Antineoplastic Agents
Survivors
Radiotherapy
Therapeutics
Drug Therapy

Keywords

  • Anesthesia
  • Chemotherapy
  • Oncology
  • Pediatric
  • Radiation therapy
  • Toxicity

ASJC Scopus subject areas

  • Anesthesiology and Pain Medicine
  • Pediatrics, Perinatology, and Child Health

Cite this

Anesthetic considerations for the pediatric oncology patient - Part 2 : Systems-based approach to anesthesia. / Latham, Gregory J.; Greenberg, Robert S.

In: Paediatric Anaesthesia, Vol. 20, No. 5, 05.2010, p. 396-420.

Research output: Contribution to journalArticle

@article{9f948c1966f0423eaf55f5847a23c0c8,
title = "Anesthetic considerations for the pediatric oncology patient - Part 2: Systems-based approach to anesthesia",
abstract = "One of the prices paid for chemo- and radiotherapy of cancer in children is damage to the vulnerable and developing healthy tissues of the body. Such damage can exist clinically or subclinically and can become apparent during active antineoplastic treatment or during remission decades later. Furthermore, effects of the tumor itself can significantly impact the physiologic state of the child. The anesthesiologist who cares for children with cancer or for survivors of childhood cancer should understand what effects cancer and its therapy can have on various organ systems. In part two of this three-part review, we review the anesthetic issues associated with childhood cancer. Specifically, this review presents a systems-based approach to the impact from both tumor and its treatment in children, followed by a discussion of the relevant anesthetic considerations.",
keywords = "Anesthesia, Chemotherapy, Oncology, Pediatric, Radiation therapy, Toxicity",
author = "Latham, {Gregory J.} and Greenberg, {Robert S}",
year = "2010",
month = "5",
doi = "10.1111/j.1460-9592.2010.03260.x",
language = "English (US)",
volume = "20",
pages = "396--420",
journal = "Paediatric Anaesthesia",
issn = "1155-5645",
publisher = "Wiley-Blackwell",
number = "5",

}

TY - JOUR

T1 - Anesthetic considerations for the pediatric oncology patient - Part 2

T2 - Systems-based approach to anesthesia

AU - Latham, Gregory J.

AU - Greenberg, Robert S

PY - 2010/5

Y1 - 2010/5

N2 - One of the prices paid for chemo- and radiotherapy of cancer in children is damage to the vulnerable and developing healthy tissues of the body. Such damage can exist clinically or subclinically and can become apparent during active antineoplastic treatment or during remission decades later. Furthermore, effects of the tumor itself can significantly impact the physiologic state of the child. The anesthesiologist who cares for children with cancer or for survivors of childhood cancer should understand what effects cancer and its therapy can have on various organ systems. In part two of this three-part review, we review the anesthetic issues associated with childhood cancer. Specifically, this review presents a systems-based approach to the impact from both tumor and its treatment in children, followed by a discussion of the relevant anesthetic considerations.

AB - One of the prices paid for chemo- and radiotherapy of cancer in children is damage to the vulnerable and developing healthy tissues of the body. Such damage can exist clinically or subclinically and can become apparent during active antineoplastic treatment or during remission decades later. Furthermore, effects of the tumor itself can significantly impact the physiologic state of the child. The anesthesiologist who cares for children with cancer or for survivors of childhood cancer should understand what effects cancer and its therapy can have on various organ systems. In part two of this three-part review, we review the anesthetic issues associated with childhood cancer. Specifically, this review presents a systems-based approach to the impact from both tumor and its treatment in children, followed by a discussion of the relevant anesthetic considerations.

KW - Anesthesia

KW - Chemotherapy

KW - Oncology

KW - Pediatric

KW - Radiation therapy

KW - Toxicity

UR - http://www.scopus.com/inward/record.url?scp=77950657493&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=77950657493&partnerID=8YFLogxK

U2 - 10.1111/j.1460-9592.2010.03260.x

DO - 10.1111/j.1460-9592.2010.03260.x

M3 - Article

C2 - 20199611

AN - SCOPUS:77950657493

VL - 20

SP - 396

EP - 420

JO - Paediatric Anaesthesia

JF - Paediatric Anaesthesia

SN - 1155-5645

IS - 5

ER -