Anesthetic considerations for the pediatric oncology patient - Part 2: Systems-based approach to anesthesia

Gregory J. Latham, Robert S. Greenberg

Research output: Contribution to journalReview articlepeer-review

Abstract

One of the prices paid for chemo- and radiotherapy of cancer in children is damage to the vulnerable and developing healthy tissues of the body. Such damage can exist clinically or subclinically and can become apparent during active antineoplastic treatment or during remission decades later. Furthermore, effects of the tumor itself can significantly impact the physiologic state of the child. The anesthesiologist who cares for children with cancer or for survivors of childhood cancer should understand what effects cancer and its therapy can have on various organ systems. In part two of this three-part review, we review the anesthetic issues associated with childhood cancer. Specifically, this review presents a systems-based approach to the impact from both tumor and its treatment in children, followed by a discussion of the relevant anesthetic considerations.

Original languageEnglish (US)
Pages (from-to)396-420
Number of pages25
JournalPaediatric anaesthesia
Volume20
Issue number5
DOIs
StatePublished - May 1 2010

Keywords

  • Anesthesia
  • Chemotherapy
  • Oncology
  • Pediatric
  • Radiation therapy
  • Toxicity

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health
  • Anesthesiology and Pain Medicine

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