Androgen replacement in menopause.

I. D. Burd, G. A. Bachmann

Research output: Contribution to journalReview articlepeer-review

Abstract

Menopause and the years leading to the menopausal transition are associated with significant decline in sex steroid levels. In contrast to the abrupt decline in estrogens at the time of menopause, a fall in the circulating testosterone and the adrenal preandrogens most closely parallel increasing age. Their accelerated decrease occurs in the years preceding menopause. It is now recognized that the decline in androgens plays a significant role in affecting perimenopausal and menopausal symptomatology and quality of life. Loss of circulating levels of androgens affects libido, vasomotor symptoms, mood and well-being, bone structure, muscle mass. Also, it influences cardiovascular profile. In the menopausal female (in whom these symptoms are clearly linked to low levels of bioavailable testosterone levels), hormone replacement therapy may be of benefit. Recently, interest is increasing in the use of androgen replacement not only for women who have undergone premature or surgical menopause but also for those who experience natural menopause and premenopausal loss of libido from diminished free testosterone.

Original languageEnglish (US)
Pages (from-to)202-205
Number of pages4
JournalCurrent women's health reports
Volume1
Issue number3
StatePublished - Dec 2001
Externally publishedYes

ASJC Scopus subject areas

  • Medicine(all)

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