Androgen-Induced Changes in the DNA Polymerase Activity of Coagulating Glands of Castrated Rats

J. A. Brasel; D. S. Coffey; H. G. Williams-Ashman

doi:10.1159/000137168

Androgen-Induced Changes in the DNA Polymerase Activity of Coagulating Glands of Castrated Rats

J. A. Brasel, D. S. Coffey, H. G. Williams-Ashman

School of Medicine

Research output: Contribution to journal › Article › peer-review

8 Scopus citations

Abstract

Large changes in Ihe activity of DNA polymerase activity occur in the soluble fraction of homogenates of the coagulating gland between the second and fifth dav after treatment of castrated rats with testosterone. These alterations in coagulating gland DNA polymerase activity are very similar to those pre viously described in the rat ventral prostate. Such androgen-induced changes in accessory gland DNA polymerase seem to be unrelated to the polyamine content of the organs. Under the same conditions, testosterone administration does not result in any early increases in DNA polymerase activity in rat levator ani muscle.

Original language	English (US)
Pages (from-to)	321-326
Number of pages	6
Journal	Pharmacology
Volume	18
Issue number	4-6
DOIs	https://doi.org/10.1159/000137168
State	Published - Jan 1 1968

ASJC Scopus subject areas

Pharmacology

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title = "Androgen-Induced Changes in the DNA Polymerase Activity of Coagulating Glands of Castrated Rats",

abstract = "Large changes in Ihe activity of DNA polymerase activity occur in the soluble fraction of homogenates of the coagulating gland between the second and fifth dav after treatment of castrated rats with testosterone. These alterations in coagulating gland DNA polymerase activity are very similar to those pre viously described in the rat ventral prostate. Such androgen-induced changes in accessory gland DNA polymerase seem to be unrelated to the polyamine content of the organs. Under the same conditions, testosterone administration does not result in any early increases in DNA polymerase activity in rat levator ani muscle.",

author = "Brasel, {J. A.} and Coffey, {D. S.} and Williams-Ashman, {H. G.}",

year = "1968",

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AU - Brasel, J. A.

AU - Coffey, D. S.

AU - Williams-Ashman, H. G.

PY - 1968/1/1

Y1 - 1968/1/1

N2 - Large changes in Ihe activity of DNA polymerase activity occur in the soluble fraction of homogenates of the coagulating gland between the second and fifth dav after treatment of castrated rats with testosterone. These alterations in coagulating gland DNA polymerase activity are very similar to those pre viously described in the rat ventral prostate. Such androgen-induced changes in accessory gland DNA polymerase seem to be unrelated to the polyamine content of the organs. Under the same conditions, testosterone administration does not result in any early increases in DNA polymerase activity in rat levator ani muscle.

AB - Large changes in Ihe activity of DNA polymerase activity occur in the soluble fraction of homogenates of the coagulating gland between the second and fifth dav after treatment of castrated rats with testosterone. These alterations in coagulating gland DNA polymerase activity are very similar to those pre viously described in the rat ventral prostate. Such androgen-induced changes in accessory gland DNA polymerase seem to be unrelated to the polyamine content of the organs. Under the same conditions, testosterone administration does not result in any early increases in DNA polymerase activity in rat levator ani muscle.

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Androgen-Induced Changes in the DNA Polymerase Activity of Coagulating Glands of Castrated Rats

Abstract

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