Anchors away! Fos fosters anchor-cell invasion

Denise J. Montell

Research output: Contribution to journalArticle

Abstract

Invasion of cells through breakdown of the basement membrane is a crucial step during development and cancer metastasis. In this issue of Cell, Sherwood et al., (2005) describe a simple and genetically tractable cellular assay in the worm for elucidating the molecular processes that underlie cell invasion in vivo. They demonstrate that the transcription factor Fos is required for cell invasion and identify three of its downstream target genes (encoding a matrix metalloproteinase, hemicentin, and a fat-like protocadherin).

Original languageEnglish (US)
Pages (from-to)816-817
Number of pages2
JournalCell
Volume121
Issue number6
DOIs
StatePublished - Jun 17 2005

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Gene encoding
Anchors
Matrix Metalloproteinases
Assays
Transcription Factors
Fats
Basement Membrane
Neoplasm Metastasis
Genes
Neoplasms

ASJC Scopus subject areas

  • Cell Biology
  • Molecular Biology

Cite this

Anchors away! Fos fosters anchor-cell invasion. / Montell, Denise J.

In: Cell, Vol. 121, No. 6, 17.06.2005, p. 816-817.

Research output: Contribution to journalArticle

Montell, Denise J. / Anchors away! Fos fosters anchor-cell invasion. In: Cell. 2005 ; Vol. 121, No. 6. pp. 816-817.
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