Anaplastic pseudothyroiditis

Shehzad Basaria, Robert Udelsman, Javier Tejedor-Sojo, William H. Westra, Alan S. Krasner

Research output: Contribution to journalArticlepeer-review

Abstract

Anaplastic thyroid carcinoma (ATC) is one of the most aggressive solid tumours. It generally presents as a rapidly enlarging thyroid mass and produces local symptoms associated with mass effect. One of the very rare presentations of ATC is thyrotoxicosis. We report a patient with ATC whose course was complicated by severe thyrotoxicosis. His symptoms were controlled with beta-blockers. Two weeks into hospitalization, the patient became hypothyroid. Histopathology showed destruction of the normal thyroid follicles by the invasion of the tumour. As this form of thyrotoxicosis resembles various thyroiditides, we hereby refer this condition as 'anaplastic pseudothyroiditis'.

Original languageEnglish (US)
Pages (from-to)553-555
Number of pages3
JournalClinical Endocrinology
Volume56
Issue number4
DOIs
StatePublished - 2002

ASJC Scopus subject areas

  • Endocrinology, Diabetes and Metabolism
  • Endocrinology

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