TY - JOUR
T1 - Anaplastic giant and spindle‐cell carcinoma of the thyroid. A different therapeutic approach
AU - Casterline, Peter F.
AU - Jaques, Darrell A.
AU - Blom, Hans
AU - Wartofsky, Leonard
PY - 1980/4/1
Y1 - 1980/4/1
N2 - The prognosis of giant and spindle cell carcinoma of the thyroid is extremely poor. It does appear, however, that a multidisciplinary approach to treatment of this aggressive cancer is more effective than a single‐treatment modality. Operative ablation of gross tumor, postoperative irradiation therapy, and chemotherapy have demonstrated encouraging results. A different therapeutic approach with the addition of immunotherapy to surgical resection, postoperative irradiation, and chemotherapy is described in this case report. The preliminary result is encouraging.
AB - The prognosis of giant and spindle cell carcinoma of the thyroid is extremely poor. It does appear, however, that a multidisciplinary approach to treatment of this aggressive cancer is more effective than a single‐treatment modality. Operative ablation of gross tumor, postoperative irradiation therapy, and chemotherapy have demonstrated encouraging results. A different therapeutic approach with the addition of immunotherapy to surgical resection, postoperative irradiation, and chemotherapy is described in this case report. The preliminary result is encouraging.
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U2 - 10.1002/1097-0142(19800401)45:7<1689::AID-CNCR2820450728>3.0.CO;2-S
DO - 10.1002/1097-0142(19800401)45:7<1689::AID-CNCR2820450728>3.0.CO;2-S
M3 - Article
C2 - 7370924
AN - SCOPUS:0018907017
SN - 0008-543X
VL - 45
SP - 1689
EP - 1692
JO - Cancer
JF - Cancer
IS - 7
ER -