Anaplasma phagocytophilum from rodents and sheep, China

Lin Zhan, Wu Chun Cao, Jia Fu Jiang, Xiao Ai Zhang, Yun Xi Liu, Xiao Ming Wu, Wen Yi Zhang, Pan He Zhang, Chang Ling Bian, J. Stephen Dumler, Hong Yang, Shu Qing Zuo, Chen Yi Chu, Wei Liu, Jan H. Richardus, J. Dik F. Habbema

Research output: Contribution to journalArticle

Abstract

To characterize the strains of Anaplasma phagocytophilum in wild and domestic animals in China, we isolated the organism from rodents and sheep in northeastern China. We isolated 3 strains (2 from rodents and 1 from sick sheep) through propagation in BALB/c mice and then cell culture in HL60 cells. The 3 isolates were identifi ed by Wright-Giemsa staining, immunofl uorescence, and electronic microscopy and were characterized by sequence analyses of the 16S rRNA gene, partial citrate synthase gene, major surface protein 4 gene, and heat shock protein gene. The multiple sequences of the 3 isolates were identical to each other but different from all known strains from other countries. The public health and veterinary relevance of the isolates deserves further investigation.

Original languageEnglish (US)
Pages (from-to)764-768
Number of pages5
JournalEmerging infectious diseases
Volume16
Issue number5
DOIs
StatePublished - May 2010

ASJC Scopus subject areas

  • Epidemiology
  • Microbiology (medical)
  • Infectious Diseases

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  • Cite this

    Zhan, L., Cao, W. C., Jiang, J. F., Zhang, X. A., Liu, Y. X., Wu, X. M., Zhang, W. Y., Zhang, P. H., Bian, C. L., Dumler, J. S., Yang, H., Zuo, S. Q., Chu, C. Y., Liu, W., Richardus, J. H., & Habbema, J. D. F. (2010). Anaplasma phagocytophilum from rodents and sheep, China. Emerging infectious diseases, 16(5), 764-768. https://doi.org/10.3201/eid1605.091293