Two patients receiving intravenous high dose methotrexate (MTX) and intracutaneous BCG injections as adjuvant treatment for osteogenic sarcoma suffered sudden cardiovascular collapse within minutes of infusion of MTX. These cases demonstrate that anaphylactic or idiosyncratic reactions to MTX and/or contaminants in these preparations do occur and that careful patient monitoring is required.
|Original language||English (US)|
|Number of pages||4|
|State||Published - Jan 1978|
ASJC Scopus subject areas
- Cancer Research