Analytical calculation of the mean time spent by photons inside an absorptive inclusion embedded in a highly scattering medium

Victor Chernomordik, David W. Hattery, Israel Gannot, Giovanni Zaccanti, Amir Gandjbakhche

Research output: Contribution to journalArticle

Abstract

The mean time spent by photons inside a nonlocalized optically abnormal embedded inclusion has been derived analytically. The accuracy of the results has been tested against Monte Carlo and experimental data. We show that for quantification of the absorption coefficient of absorptive inclusions, a corrective factor that takes into account the size of the inclusion is needed. This finding suggests that perturbation methods derived for very small inclusions which are used in inverse algorithms require a corrective factor to adequately quantify the differential absorption coefficient of nonlocalized targets embedded in optically turbid media.

Original languageEnglish (US)
Pages (from-to)486-492
Number of pages7
JournalJournal of biomedical optics
Volume7
Issue number3
DOIs
StatePublished - Jul 2002
Externally publishedYes

Keywords

  • Differential absorption
  • Optical imaging
  • Photon migration
  • Time of flight

ASJC Scopus subject areas

  • Electronic, Optical and Magnetic Materials
  • Biomaterials
  • Atomic and Molecular Physics, and Optics
  • Biomedical Engineering

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