Analytic system matrix resolution modeling in PET: An application to Rb-82 cardiac imaging

A. Rahmim, M. A. Lodge, J. Tang, S. Lashkari, M. R. Ay

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

An area of growing interest in PET imaging has been that of incorporating increasingly more accurate system matrix elements into the reconstruction task, thus arriving at images of higher quality. This work explores application of an analytic approach which individually models and combines the various resolution degrading phenomenon in PET (inter-crystal scattering, inter-crystal penetration, photon non-collinearity and positron range), and does not require extensive experimental measurements and/or simulations. The approach is able to produce considerable enhancements in image quality. The reconstructed resolution is seen to improve from 5.1mm-7.7mm across the field-of-view (FoV) to ≈3.5mm nearly uniformly across the FoV. Furthermore, phantom studies indicate clearly improved images, while similar significant improvements are seen for the particular task of Rb-82 cardiac imaging.

Original languageEnglish (US)
Title of host publication2008 5th IEEE International Symposium on Biomedical Imaging
Subtitle of host publicationFrom Nano to Macro, Proceedings, ISBI
Pages1307-1310
Number of pages4
DOIs
StatePublished - Sep 10 2008
Event2008 5th IEEE International Symposium on Biomedical Imaging: From Nano to Macro, ISBI - Paris, France
Duration: May 14 2008May 17 2008

Publication series

Name2008 5th IEEE International Symposium on Biomedical Imaging: From Nano to Macro, Proceedings, ISBI

Other

Other2008 5th IEEE International Symposium on Biomedical Imaging: From Nano to Macro, ISBI
CountryFrance
CityParis
Period5/14/085/17/08

Keywords

  • Compton scattering
  • Image enhancement
  • Image reconstruction
  • Positron emission tomography
  • Positrons

ASJC Scopus subject areas

  • Biomedical Engineering

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