Analysis of potassium titanyl phosphate laser settings and voice outcomes in the treatment of Reinke's edema

Vyvy N. Young, Pavan S. Mallur, Adrienne W. Wong, Rajarsi Mandal, Giuseppe V. Staltari, Jackie Gartner-Schmidt, Clark A. Rosen

Research output: Contribution to journalArticle

Abstract

Objective: Despite increased clinical utility of the 532-nm potassium titanyl phosphate (KTP) laser, no studies have examined outcomes for Reinke's edema (RE) as a function of laser parameters and initial treatment effects. Variability in delivery parameters, fiber-to-tissue distance, and immediate end-tissue effects limits universal application of existing study outcomes. We examine voice outcomes using standardized treatment classification, providing justification for laser parameter selection and immediate tissue effect in clinical use. Methods: Retrospective review of 9 patients who underwent KTP laser treatment for RE. Demographics, RE severity, laser settings, total laser energy, and immediate tissue effects were correlated with quantified voice outcomes. Results: An average of 157 joules (6-640 J) was delivered over a 0.369-second exposure time (0.1-0.9 seconds). Immediate tissue effects varied from nonablative treatment (type I and type II) to ablation without tissue removal (type III). Overall, Voice Handicap Index-10 (VHI-10) decreased by 8.23; improvement was most pronounced with type II treatments (delta VHI-10 = 12). No complications were encountered. Conclusion: Potassium titanyl phosphate laser can be safely and effectively used to improve voice in RE patients regardless of severity. This is the first study to provide detailed information on laser settings, energy delivery, and treatment effect in RE management; these results may guide clinical use of this modality, especially for novice laser surgeons.

Original languageEnglish (US)
Pages (from-to)216-220
Number of pages5
JournalAnnals of Otology, Rhinology and Laryngology
Volume124
Issue number3
DOIs
StatePublished - Mar 1 2015
Externally publishedYes

Fingerprint

Solid-State Lasers
Edema
Lasers
Therapeutics
Demography
Outcome Assessment (Health Care)

Keywords

  • KTP
  • laser
  • outcome
  • Reinke's edema
  • surgery
  • voice

ASJC Scopus subject areas

  • Otorhinolaryngology

Cite this

Analysis of potassium titanyl phosphate laser settings and voice outcomes in the treatment of Reinke's edema. / Young, Vyvy N.; Mallur, Pavan S.; Wong, Adrienne W.; Mandal, Rajarsi; Staltari, Giuseppe V.; Gartner-Schmidt, Jackie; Rosen, Clark A.

In: Annals of Otology, Rhinology and Laryngology, Vol. 124, No. 3, 01.03.2015, p. 216-220.

Research output: Contribution to journalArticle

Young, Vyvy N. ; Mallur, Pavan S. ; Wong, Adrienne W. ; Mandal, Rajarsi ; Staltari, Giuseppe V. ; Gartner-Schmidt, Jackie ; Rosen, Clark A. / Analysis of potassium titanyl phosphate laser settings and voice outcomes in the treatment of Reinke's edema. In: Annals of Otology, Rhinology and Laryngology. 2015 ; Vol. 124, No. 3. pp. 216-220.
@article{8b8f5617fb2e4d6fa2045fb02b958dfa,
title = "Analysis of potassium titanyl phosphate laser settings and voice outcomes in the treatment of Reinke's edema",
abstract = "Objective: Despite increased clinical utility of the 532-nm potassium titanyl phosphate (KTP) laser, no studies have examined outcomes for Reinke's edema (RE) as a function of laser parameters and initial treatment effects. Variability in delivery parameters, fiber-to-tissue distance, and immediate end-tissue effects limits universal application of existing study outcomes. We examine voice outcomes using standardized treatment classification, providing justification for laser parameter selection and immediate tissue effect in clinical use. Methods: Retrospective review of 9 patients who underwent KTP laser treatment for RE. Demographics, RE severity, laser settings, total laser energy, and immediate tissue effects were correlated with quantified voice outcomes. Results: An average of 157 joules (6-640 J) was delivered over a 0.369-second exposure time (0.1-0.9 seconds). Immediate tissue effects varied from nonablative treatment (type I and type II) to ablation without tissue removal (type III). Overall, Voice Handicap Index-10 (VHI-10) decreased by 8.23; improvement was most pronounced with type II treatments (delta VHI-10 = 12). No complications were encountered. Conclusion: Potassium titanyl phosphate laser can be safely and effectively used to improve voice in RE patients regardless of severity. This is the first study to provide detailed information on laser settings, energy delivery, and treatment effect in RE management; these results may guide clinical use of this modality, especially for novice laser surgeons.",
keywords = "KTP, laser, outcome, Reinke's edema, surgery, voice",
author = "Young, {Vyvy N.} and Mallur, {Pavan S.} and Wong, {Adrienne W.} and Rajarsi Mandal and Staltari, {Giuseppe V.} and Jackie Gartner-Schmidt and Rosen, {Clark A.}",
year = "2015",
month = "3",
day = "1",
doi = "10.1177/0003489414549155",
language = "English (US)",
volume = "124",
pages = "216--220",
journal = "Annals of Otology, Rhinology and Laryngology",
issn = "0003-4894",
publisher = "Annals Publishing Company",
number = "3",

}

TY - JOUR

T1 - Analysis of potassium titanyl phosphate laser settings and voice outcomes in the treatment of Reinke's edema

AU - Young, Vyvy N.

AU - Mallur, Pavan S.

AU - Wong, Adrienne W.

AU - Mandal, Rajarsi

AU - Staltari, Giuseppe V.

AU - Gartner-Schmidt, Jackie

AU - Rosen, Clark A.

PY - 2015/3/1

Y1 - 2015/3/1

N2 - Objective: Despite increased clinical utility of the 532-nm potassium titanyl phosphate (KTP) laser, no studies have examined outcomes for Reinke's edema (RE) as a function of laser parameters and initial treatment effects. Variability in delivery parameters, fiber-to-tissue distance, and immediate end-tissue effects limits universal application of existing study outcomes. We examine voice outcomes using standardized treatment classification, providing justification for laser parameter selection and immediate tissue effect in clinical use. Methods: Retrospective review of 9 patients who underwent KTP laser treatment for RE. Demographics, RE severity, laser settings, total laser energy, and immediate tissue effects were correlated with quantified voice outcomes. Results: An average of 157 joules (6-640 J) was delivered over a 0.369-second exposure time (0.1-0.9 seconds). Immediate tissue effects varied from nonablative treatment (type I and type II) to ablation without tissue removal (type III). Overall, Voice Handicap Index-10 (VHI-10) decreased by 8.23; improvement was most pronounced with type II treatments (delta VHI-10 = 12). No complications were encountered. Conclusion: Potassium titanyl phosphate laser can be safely and effectively used to improve voice in RE patients regardless of severity. This is the first study to provide detailed information on laser settings, energy delivery, and treatment effect in RE management; these results may guide clinical use of this modality, especially for novice laser surgeons.

AB - Objective: Despite increased clinical utility of the 532-nm potassium titanyl phosphate (KTP) laser, no studies have examined outcomes for Reinke's edema (RE) as a function of laser parameters and initial treatment effects. Variability in delivery parameters, fiber-to-tissue distance, and immediate end-tissue effects limits universal application of existing study outcomes. We examine voice outcomes using standardized treatment classification, providing justification for laser parameter selection and immediate tissue effect in clinical use. Methods: Retrospective review of 9 patients who underwent KTP laser treatment for RE. Demographics, RE severity, laser settings, total laser energy, and immediate tissue effects were correlated with quantified voice outcomes. Results: An average of 157 joules (6-640 J) was delivered over a 0.369-second exposure time (0.1-0.9 seconds). Immediate tissue effects varied from nonablative treatment (type I and type II) to ablation without tissue removal (type III). Overall, Voice Handicap Index-10 (VHI-10) decreased by 8.23; improvement was most pronounced with type II treatments (delta VHI-10 = 12). No complications were encountered. Conclusion: Potassium titanyl phosphate laser can be safely and effectively used to improve voice in RE patients regardless of severity. This is the first study to provide detailed information on laser settings, energy delivery, and treatment effect in RE management; these results may guide clinical use of this modality, especially for novice laser surgeons.

KW - KTP

KW - laser

KW - outcome

KW - Reinke's edema

KW - surgery

KW - voice

UR - http://www.scopus.com/inward/record.url?scp=84930388306&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84930388306&partnerID=8YFLogxK

U2 - 10.1177/0003489414549155

DO - 10.1177/0003489414549155

M3 - Article

VL - 124

SP - 216

EP - 220

JO - Annals of Otology, Rhinology and Laryngology

JF - Annals of Otology, Rhinology and Laryngology

SN - 0003-4894

IS - 3

ER -