Analysis of expression patterns: The scope of the problem, the problem of scope

Yidong Chen, Zohar Yakhini, Amir Ben-Dor, Edward Dougherty, Jeffrey M. Trent, Michael Bittner

Research output: Contribution to journalArticlepeer-review

Abstract

Studies of the expression patterns of many genes simultaneously lead to the observation that even in closely related pathologies, there are numerous genes that are differentially expressed in consistent patterns correlated to each sample type. The early uses of the enabling technology, microarrays, was focused on gathering mechanistic biological insights. The early findings now pose another clear challenge, finding ways to effectively use this kind of information to develop diagnostics.

Original languageEnglish (US)
Pages (from-to)59-65
Number of pages7
JournalDisease Markers
Volume17
Issue number2
DOIs
StatePublished - 2001

ASJC Scopus subject areas

  • Molecular Biology
  • Genetics
  • Clinical Biochemistry
  • Biochemistry, medical

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