Analysis of excess lung cancer risk en short-term employees

Steven H. Lamm, Marshal S. Levine, Jennifer A. Starr, Sandra L. Tirey

Research output: Contribution to journalArticle

Abstract

An excess of lung cancer found in a cohort of 741 New York State tremolitic talc workers observed from 1947 through 1978 has been shown paradoxically to be concentrated in short-term workers. Review of past work histories suggests that the excess of lung cancer in these short-term workers may be accounted for by prior exposures rather than by exposures at the employment under investigation. This finding has significant implications in view of the developing practice of including short-term workers in occupational cohort studies In contrast to the more traditional practice of excluding short-term workers. The traditional practice was based on the assumption that the inclusion of short-term workers with little exposure, and thus little risk, might dilute an otherwise apparent association between mortality and exposure. This study suggests that in certain instances the inclusion of short-term workers may magnify rather than dilute the estimation of risk, reflecting the presence of confounding variables.

Original languageEnglish (US)
Pages (from-to)1202-1209
Number of pages8
JournalAmerican Journal of Epidemiology
Volume127
Issue number6
StatePublished - Jun 1988
Externally publishedYes

Keywords

  • Lung diseases
  • Lung neoplasms
  • Occupational diseases
  • Talc

ASJC Scopus subject areas

  • Geriatrics and Gerontology
  • Epidemiology

Fingerprint Dive into the research topics of 'Analysis of excess lung cancer risk en short-term employees'. Together they form a unique fingerprint.

  • Cite this

    Lamm, S. H., Levine, M. S., Starr, J. A., & Tirey, S. L. (1988). Analysis of excess lung cancer risk en short-term employees. American Journal of Epidemiology, 127(6), 1202-1209.