Análisis del consumo de antibióticos en la población pediátrica de Castilla y León durante el período 2001 a 2005

Translated title of the contribution: Analysis of antibiotic consumption in the pediatric population of Castile and León (Spain) from 2001 to 2005

M. E. Vázquez Fernández, F. J. Luquero Alcalde, E. Pastor García, M. R. Bachiller Luque, M. J. Vázquez Fernández, J. M. Eiros Bouza

Research output: Contribution to journalArticlepeer-review

Abstract

Objectives: To analyze trends in antibiotic use among the pediatric population of Castile and León from 2001 to 2005. Material and methods: The antibiotics prescribed to the pediatric population in primary care were processed using the CONCYLIA database. The technical unit of measurement was the defined daily dose (DDD) and the comparative indicator used was the DDD per 1000 inhabitants/day (DID). Results: Overall consumption was high (21.21 DID). Throughout the 5 years of the study we observed substantial variations, especially in 2005, the year in which consumption was highest (25.05 DID). The therapeutic subgroups most frequently prescribed were wide-spectrum penicillins (8.08 DID) and penicillins associated with beta-lactamase inhibitors (7.29 DID), followed by cephalosporins (2.81 DHD) and macrolides (2.52 DHD). The percentage of wide-spectrum penicillin prescription was higher than that of penicillins associated with beta-lactamase inhibitors between 2001 and 2002. These percentages were similar in 2003, and the percentage of wide-spectrum penicillin prescription was lower than that of penicillins associated with beta-lactamase inhibitors in the last 2 years of the study. Conclusions: Marked differences in consumption were observed over the study period. Changes in patterns of use were found, with an increase in the use of penicillins associated with beta-lactamase inhibitors in the last 2 years of the study.

Translated title of the contributionAnalysis of antibiotic consumption in the pediatric population of Castile and León (Spain) from 2001 to 2005
Original languageSpanish
Pages (from-to)11-17
Number of pages7
JournalAnales de Pediatria
Volume67
Issue number1
DOIs
StatePublished - Jul 1 2007
Externally publishedYes

Keywords

  • Antibiotics
  • Pharmacoepidemiologic study
  • Primary care

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health

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