Analysis of a polytef granuloma mimicking a cold thyroid nodule 17 months after laryngeal injection

Fred Sanfilippo; John Sheiburne; Peter Ingram

doi:10.3109/01913128009140553

Analysis of a polytef granuloma mimicking a cold thyroid nodule 17 months after laryngeal injection

Fred Sanfilippo, John Sheiburne, Peter Ingram

Research output: Contribution to journal › Article › peer-review

8 Scopus citations

Abstract

A 65-year-old female who received laryngeal injections with polytef (Teflon) paste for treatment of right vocal cord paralysis first noticed a small, right anterior neck mass 17 months later. Clinically this mass slowly progressed in size and was felt to be a recurrent carotid body tumor, but at surgery, 22 months after injection, a circumscribed nodule on the anterior right lobe of the thyroid was found and histologically diag-nosed as a foreign body granuloma. Scanning electron microscopy (SEM) and energy-dispersive x-ray analysis (EDXA) of material in this lesion was identical to that of polytef paste, which is a mixture of pyrolyzed poly-tetrafluoroethylene and glycerine. The possibility that deaggregated smaller particles in the polytef paste were able to migrate from the injection site resulting in this neck mass is considered.

Original language	English (US)
Pages (from-to)	471-475
Number of pages	5
Journal	Ultrastructural Pathology
Volume	1
Issue number	4
DOIs	https://doi.org/10.3109/01913128009140553
State	Published - 1980
Externally published	Yes

Keywords

Energy-dispersive x-ray analysis (EDXA)
Fluorine
Granuloma
Polytef
Thyroid nodule

ASJC Scopus subject areas

Pathology and Forensic Medicine
Structural Biology
Instrumentation

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10.3109/01913128009140553

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title = "Analysis of a polytef granuloma mimicking a cold thyroid nodule 17 months after laryngeal injection",

abstract = "A 65-year-old female who received laryngeal injections with polytef (Teflon) paste for treatment of right vocal cord paralysis first noticed a small, right anterior neck mass 17 months later. Clinically this mass slowly progressed in size and was felt to be a recurrent carotid body tumor, but at surgery, 22 months after injection, a circumscribed nodule on the anterior right lobe of the thyroid was found and histologically diag-nosed as a foreign body granuloma. Scanning electron microscopy (SEM) and energy-dispersive x-ray analysis (EDXA) of material in this lesion was identical to that of polytef paste, which is a mixture of pyrolyzed poly-tetrafluoroethylene and glycerine. The possibility that deaggregated smaller particles in the polytef paste were able to migrate from the injection site resulting in this neck mass is considered.",

keywords = "Energy-dispersive x-ray analysis (EDXA), Fluorine, Granuloma, Polytef, Thyroid nodule",

author = "Fred Sanfilippo and John Sheiburne and Peter Ingram",

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doi = "10.3109/01913128009140553",

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T1 - Analysis of a polytef granuloma mimicking a cold thyroid nodule 17 months after laryngeal injection

AU - Sanfilippo, Fred

AU - Sheiburne, John

AU - Ingram, Peter

PY - 1980

Y1 - 1980

N2 - A 65-year-old female who received laryngeal injections with polytef (Teflon) paste for treatment of right vocal cord paralysis first noticed a small, right anterior neck mass 17 months later. Clinically this mass slowly progressed in size and was felt to be a recurrent carotid body tumor, but at surgery, 22 months after injection, a circumscribed nodule on the anterior right lobe of the thyroid was found and histologically diag-nosed as a foreign body granuloma. Scanning electron microscopy (SEM) and energy-dispersive x-ray analysis (EDXA) of material in this lesion was identical to that of polytef paste, which is a mixture of pyrolyzed poly-tetrafluoroethylene and glycerine. The possibility that deaggregated smaller particles in the polytef paste were able to migrate from the injection site resulting in this neck mass is considered.

AB - A 65-year-old female who received laryngeal injections with polytef (Teflon) paste for treatment of right vocal cord paralysis first noticed a small, right anterior neck mass 17 months later. Clinically this mass slowly progressed in size and was felt to be a recurrent carotid body tumor, but at surgery, 22 months after injection, a circumscribed nodule on the anterior right lobe of the thyroid was found and histologically diag-nosed as a foreign body granuloma. Scanning electron microscopy (SEM) and energy-dispersive x-ray analysis (EDXA) of material in this lesion was identical to that of polytef paste, which is a mixture of pyrolyzed poly-tetrafluoroethylene and glycerine. The possibility that deaggregated smaller particles in the polytef paste were able to migrate from the injection site resulting in this neck mass is considered.

KW - Energy-dispersive x-ray analysis (EDXA)

KW - Fluorine

KW - Granuloma

KW - Polytef

KW - Thyroid nodule

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Analysis of a polytef granuloma mimicking a cold thyroid nodule 17 months after laryngeal injection

Abstract

Keywords

ASJC Scopus subject areas

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