Analgesics and chronic renal disease

Michael J. Klag, Paul K. Whelton, Thomas V. Perneger

Research output: Contribution to journalReview articlepeer-review

Abstract

Intake of analgesics has been associated with the presence of chronic renal diseases in a number of studies, Phenacetin was the first drug to be linked with chronic renal disease. Four out of five case-control studies that have examined this issue have also demonstrated an association of acetaminophen use with renal disease. Nonsteroidal anti-inflammatory drugs have not been available for a long enough time to evaluate risk associated with their use. Several studies suggest that mixtures of analgesics are most harmful to the Kidney. The National Kidney Foundation recently issued a position paper on analgesics and the kidney that provides guidance to patients and providers.

Original languageEnglish (US)
Pages (from-to)236-241
Number of pages6
JournalCurrent opinion in nephrology and hypertension
Volume5
Issue number3
DOIs
StatePublished - 1996

ASJC Scopus subject areas

  • Internal Medicine
  • Nephrology

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