Anal human papillomavirus (HPV) is prevalent among men who have sex with men (MSM), but has not been studied in the Russian Federation. A cross-sectional survey and HPV genotyping were conducted among HIV seropositive (n=58) and seronegative MSM (n=65) in Moscow. Multivariable logistic regression was performed to identify correlates of infection with onco-genic HPV genotypes 16 and/or 18 (HPV 16/18). Forty per cent (49/124) of all MSM were infected with at least one anal HPV genotype, 31.5% (39/124) had HPV16/18, and 11.5% (14/121) had high-grade squamous intraepi-thelial lesions (HSIL). HPV 16/18 was more prevalent in HIV seropositive than seronegative men (24/58, 41.4% vs 15/65, 23.1%; p=0.03). HIV infection was independently associated with HPV 16/18 (adjusted odds ratio (AOR): 5.08; 95% confidence intervals (CI): 1.49–17.34, p=0.01), as was having 2–4 steady male sex partners in the last year (vs ≤ 1 partner; AOR: 6.99; 95%CI: 1.94–25.24, p<0.01). History of prison/detention, migration to/within Russia and use of incompatible lubricants were marginally associated with HPV 16/18 (p<0.10). Comprehensive prevention options are needed to address HIV and HPV infection among MSM in Russia and may benefit from inclusion of young men in piloted HPV vaccination programmes.
|Original language||English (US)|
|Number of pages||10|
|State||Published - 2015|
ASJC Scopus subject areas
- Public Health, Environmental and Occupational Health