Anal duct carcinoma in a 70-year-old male with a history of prostate cancer

Zina Meriden; Elizabeth A. Montgomery

doi:10.1016/j.mpdhp.2011.06.005

Anal duct carcinoma in a 70-year-old male with a history of prostate cancer

Zina Meriden, Elizabeth A. Montgomery

School of Medicine

Research output: Contribution to journal › Article › peer-review

1 Scopus citations

Abstract

Anal duct (gland) carcinoma is a rare, under-recognized neoplasm of the anal canal. Histologically, it consists of haphazardly oriented neoplastic glands that proliferate beneath intact non-neoplastic squamous epithelium. Frequently, Pagetoid-like spread into the overlying squamous epithelium may be observed. Anal duct carcinoma is characteristically CK7+/CK20- by immunohistochemistry. We report a case of anal duct carcinoma diagnosed in a 70-year-old male with a history of treated prostate cancer. The epidemiology, clinical presentation, histologic features, differential diagnosis, treatment, and prognosis of anal duct carcinoma are discussed.

Original language	English (US)
Pages (from-to)	362-365
Number of pages	4
Journal	Diagnostic Histopathology
Volume	17
Issue number	8
DOIs	https://doi.org/10.1016/j.mpdhp.2011.06.005
State	Published - Aug 1 2011

Keywords

Anal duct carcinoma
Anal gland carcinoma

ASJC Scopus subject areas

Pathology and Forensic Medicine
Histology

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10.1016/j.mpdhp.2011.06.005

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title = "Anal duct carcinoma in a 70-year-old male with a history of prostate cancer",

abstract = "Anal duct (gland) carcinoma is a rare, under-recognized neoplasm of the anal canal. Histologically, it consists of haphazardly oriented neoplastic glands that proliferate beneath intact non-neoplastic squamous epithelium. Frequently, Pagetoid-like spread into the overlying squamous epithelium may be observed. Anal duct carcinoma is characteristically CK7+/CK20- by immunohistochemistry. We report a case of anal duct carcinoma diagnosed in a 70-year-old male with a history of treated prostate cancer. The epidemiology, clinical presentation, histologic features, differential diagnosis, treatment, and prognosis of anal duct carcinoma are discussed.",

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AU - Montgomery, Elizabeth A.

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N2 - Anal duct (gland) carcinoma is a rare, under-recognized neoplasm of the anal canal. Histologically, it consists of haphazardly oriented neoplastic glands that proliferate beneath intact non-neoplastic squamous epithelium. Frequently, Pagetoid-like spread into the overlying squamous epithelium may be observed. Anal duct carcinoma is characteristically CK7+/CK20- by immunohistochemistry. We report a case of anal duct carcinoma diagnosed in a 70-year-old male with a history of treated prostate cancer. The epidemiology, clinical presentation, histologic features, differential diagnosis, treatment, and prognosis of anal duct carcinoma are discussed.

AB - Anal duct (gland) carcinoma is a rare, under-recognized neoplasm of the anal canal. Histologically, it consists of haphazardly oriented neoplastic glands that proliferate beneath intact non-neoplastic squamous epithelium. Frequently, Pagetoid-like spread into the overlying squamous epithelium may be observed. Anal duct carcinoma is characteristically CK7+/CK20- by immunohistochemistry. We report a case of anal duct carcinoma diagnosed in a 70-year-old male with a history of treated prostate cancer. The epidemiology, clinical presentation, histologic features, differential diagnosis, treatment, and prognosis of anal duct carcinoma are discussed.

KW - Anal duct carcinoma

KW - Anal gland carcinoma

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Anal duct carcinoma in a 70-year-old male with a history of prostate cancer

Abstract

Keywords

ASJC Scopus subject areas

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