Anaerobic flora of the conjunctival sac in patients with AIDS and with anophthalmia compared with normal eyes

M. S. De Queiroz Campos, D. L. De Queiroz Campos e Silva, J. R C L Rehder, M. B. Lee, T. O'Brien, Peter J McDonnell

Research output: Contribution to journalArticle

Abstract

Relatively few investigations of anaerobic bacteria as ocular flora have been conducted, and their results have been contradictory. The conjunctival sacs of 22 normal subjects and of 14 patients with acquired immunodeficiency syndrome, and 22 anophthalmic sockets were cultured for anaerobic bacteria. Thirty-four (77.3%) of the 44 eyes of normal subjects harbored anaerobic bacteria; Propionibacterium acnes was present in 28 eyes (63.6%), Lactobacillus species in 6 eyes (13.6%), and Veillonella species in 7 eyes (15.9%). The finding were very similar for anophthalmic sockets (p = 0.01), with 17 (77.3%) of the 22 sockets harboring anaerobes; Propionibacterium acnes was the organism identified in 16 (72.7%) of these sockets; Veillonella was identified in 4 (18.1%), Peptococcus niger in 3 (13.6%) and P. granulosum in 2 (9.0%) of these sockets. Acquired immunodeficiency syndrome patients had the highest incidence of anaerobic organisms, with positive cultures obtained from 24 (85.7%) of the 28 eyes. Propionibacterium species were isolated from 16 (57.1%) of these eyes, Clostridium species from 10 (35.7%) eyes and Actinomyces species from 8 (28.6%) eyes. It thus appears that anaerobic organisms are common flora in normal conjunctival sacs and in anophthalmic sockets, as well as in the sacs of acquired immunodeficiency syndrome patients, but the latter group had a higher incidence (x2 = 0.87) and a spectrum of organisms that was different from that of the other two groups.

Original languageEnglish (US)
Pages (from-to)241-245
Number of pages5
JournalActa Ophthalmologica
Volume72
Issue number2
StatePublished - 1994
Externally publishedYes

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Anophthalmos
Lacrimal Apparatus
Acquired Immunodeficiency Syndrome
Anaerobic Bacteria
Veillonella
Propionibacterium acnes
Peptococcus
Propionibacterium
Actinomyces
Clostridium
Incidence
Lactobacillus

Keywords

  • AIDS
  • Anaerobic bacteria
  • Anophthalmic cavities
  • Bacterial flora
  • Ocular pathogens

ASJC Scopus subject areas

  • Ophthalmology

Cite this

De Queiroz Campos, M. S., De Queiroz Campos e Silva, D. L., Rehder, J. R. C. L., Lee, M. B., O'Brien, T., & McDonnell, P. J. (1994). Anaerobic flora of the conjunctival sac in patients with AIDS and with anophthalmia compared with normal eyes. Acta Ophthalmologica, 72(2), 241-245.

Anaerobic flora of the conjunctival sac in patients with AIDS and with anophthalmia compared with normal eyes. / De Queiroz Campos, M. S.; De Queiroz Campos e Silva, D. L.; Rehder, J. R C L; Lee, M. B.; O'Brien, T.; McDonnell, Peter J.

In: Acta Ophthalmologica, Vol. 72, No. 2, 1994, p. 241-245.

Research output: Contribution to journalArticle

De Queiroz Campos, MS, De Queiroz Campos e Silva, DL, Rehder, JRCL, Lee, MB, O'Brien, T & McDonnell, PJ 1994, 'Anaerobic flora of the conjunctival sac in patients with AIDS and with anophthalmia compared with normal eyes', Acta Ophthalmologica, vol. 72, no. 2, pp. 241-245.
De Queiroz Campos MS, De Queiroz Campos e Silva DL, Rehder JRCL, Lee MB, O'Brien T, McDonnell PJ. Anaerobic flora of the conjunctival sac in patients with AIDS and with anophthalmia compared with normal eyes. Acta Ophthalmologica. 1994;72(2):241-245.
De Queiroz Campos, M. S. ; De Queiroz Campos e Silva, D. L. ; Rehder, J. R C L ; Lee, M. B. ; O'Brien, T. ; McDonnell, Peter J. / Anaerobic flora of the conjunctival sac in patients with AIDS and with anophthalmia compared with normal eyes. In: Acta Ophthalmologica. 1994 ; Vol. 72, No. 2. pp. 241-245.
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abstract = "Relatively few investigations of anaerobic bacteria as ocular flora have been conducted, and their results have been contradictory. The conjunctival sacs of 22 normal subjects and of 14 patients with acquired immunodeficiency syndrome, and 22 anophthalmic sockets were cultured for anaerobic bacteria. Thirty-four (77.3{\%}) of the 44 eyes of normal subjects harbored anaerobic bacteria; Propionibacterium acnes was present in 28 eyes (63.6{\%}), Lactobacillus species in 6 eyes (13.6{\%}), and Veillonella species in 7 eyes (15.9{\%}). The finding were very similar for anophthalmic sockets (p = 0.01), with 17 (77.3{\%}) of the 22 sockets harboring anaerobes; Propionibacterium acnes was the organism identified in 16 (72.7{\%}) of these sockets; Veillonella was identified in 4 (18.1{\%}), Peptococcus niger in 3 (13.6{\%}) and P. granulosum in 2 (9.0{\%}) of these sockets. Acquired immunodeficiency syndrome patients had the highest incidence of anaerobic organisms, with positive cultures obtained from 24 (85.7{\%}) of the 28 eyes. Propionibacterium species were isolated from 16 (57.1{\%}) of these eyes, Clostridium species from 10 (35.7{\%}) eyes and Actinomyces species from 8 (28.6{\%}) eyes. It thus appears that anaerobic organisms are common flora in normal conjunctival sacs and in anophthalmic sockets, as well as in the sacs of acquired immunodeficiency syndrome patients, but the latter group had a higher incidence (x2 = 0.87) and a spectrum of organisms that was different from that of the other two groups.",
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