An update on cardiovascular disease epidemiology in South East Asia. Rationale and design of the LIFE course study in CARdiovascular disease Epidemiology (LIFECARE)

E. Shyong Tai, Richie Poulton, Julian Thumboo, Rody Sy, Nina Castillo-Carandang, Piyamitr Sritara, John M.F. Adam, Kui Hian Sim, Alan Fong, Hwee Lin Wee, Mark Woodward

Research output: Contribution to journalArticle

Abstract

The burden of cardiovascular disease (CVD) is likely to increase dramatically in Asia over the next several decades. In this paper, we review the existing data on CVD epidemiology in Asia, with a focus on the INTERHEART study and the Asia Pacific Cohort Studies Collaboration. Existing data suggests that much of CVD may be preventable through reduction in the levels of well-established CVD risk factors and that these findings are likely to be relevant to Asian populations. However, these studies have several important limitations. These include a lack of longitudinal studies with collection of repeated measures of CVD risk factors and the environmental factors that may result in the age-related increase in the levels of these risk factors. As such, the natural history of the development of CVD risk factors such as obesity, diabetes, hypertension and dyslipidemia in Asia, and their relationship in terms of duration and timing of exposure to various environmental influences is currently unknown. In addition, there is a paucity of data related to psychosocial factors that may be involved in the pathogenesis of CVD, either directly or through effects on other CVD risk factors. Finally, little data is available with regards to the impact of CVD and its attendant risk factors on health related quality of life and health care utilization. This information is crucial for the design and evaluation of evidence based programs for primary prevention. We have designed a LIFE Course Study in CARdiovascular disease Epidemiology (LIFECARE) involving 12,000 individuals in four South East Asian countries to address these data needs.

Original languageEnglish (US)
Pages (from-to)93-102
Number of pages10
JournalCVD Prevention and Control
Volume4
Issue number2
DOIs
StatePublished - Jun 1 2009

Keywords

  • Asia
  • Cardiovascular disease
  • Health care utilization
  • Life course epidemiology
  • Psychosocial factors
  • Quality of life

ASJC Scopus subject areas

  • Epidemiology
  • Community and Home Care
  • Cardiology and Cardiovascular Medicine

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  • Cite this

    Tai, E. S., Poulton, R., Thumboo, J., Sy, R., Castillo-Carandang, N., Sritara, P., Adam, J. M. F., Sim, K. H., Fong, A., Wee, H. L., & Woodward, M. (2009). An update on cardiovascular disease epidemiology in South East Asia. Rationale and design of the LIFE course study in CARdiovascular disease Epidemiology (LIFECARE). CVD Prevention and Control, 4(2), 93-102. https://doi.org/10.1016/j.cvdpc.2009.02.003