An oocyte donation protocol using the GnRH antagonist ganirelix acetate, does not compromise embryo quality and is associated with high pregnancy rates

N. F. Vlahos, B. J. Bankowski, Howard A Zacur, Jairo Garcia, Edward E Wallach, Y. Zhao

Research output: Contribution to journalArticle

Abstract

Purpose: To evaluate the effect of the GnRH antagonist, ganirelix acetate, on oocyte quality. Methods: Stimulation characteristics, implantation rates and clinical pregnancy rates were compared between 29 oocyte donors 21-31 years of age who underwent 31 cycles of ovarian stimulation with gonadotropins and ganirelix acetate, and 36 infertile couples of similar age range who underwent 51 cycles of ovarian stimulation using the same protocol. Results: A significantly lower number of embryos were transferred in the donor/recipient group as compared to the infertile group (2.32±0.54 vs. 2.82±0.71, P

Original languageEnglish (US)
Pages (from-to)1-6
Number of pages6
JournalArchives of Gynecology and Obstetrics
Volume272
Issue number1
DOIs
StatePublished - Jun 2005

Fingerprint

Oocyte Donation
Ovulation Induction
Pregnancy Rate
Gonadotropin-Releasing Hormone
Oocytes
Embryonic Structures
Gonadotropins
ganirelix

Keywords

  • Ganirelix acetate
  • GnRH antagonist
  • IVF
  • Oocyte donor

ASJC Scopus subject areas

  • Obstetrics and Gynecology

Cite this

@article{c6b0b87e238a44cf88247058f03335bc,
title = "An oocyte donation protocol using the GnRH antagonist ganirelix acetate, does not compromise embryo quality and is associated with high pregnancy rates",
abstract = "Purpose: To evaluate the effect of the GnRH antagonist, ganirelix acetate, on oocyte quality. Methods: Stimulation characteristics, implantation rates and clinical pregnancy rates were compared between 29 oocyte donors 21-31 years of age who underwent 31 cycles of ovarian stimulation with gonadotropins and ganirelix acetate, and 36 infertile couples of similar age range who underwent 51 cycles of ovarian stimulation using the same protocol. Results: A significantly lower number of embryos were transferred in the donor/recipient group as compared to the infertile group (2.32±0.54 vs. 2.82±0.71, P",
keywords = "Ganirelix acetate, GnRH antagonist, IVF, Oocyte donor",
author = "Vlahos, {N. F.} and Bankowski, {B. J.} and Zacur, {Howard A} and Jairo Garcia and Wallach, {Edward E} and Y. Zhao",
year = "2005",
month = "6",
doi = "10.1007/s00404-005-0726-2",
language = "English (US)",
volume = "272",
pages = "1--6",
journal = "Archives of Gynecology and Obstetrics",
issn = "0932-0067",
publisher = "Springer Verlag",
number = "1",

}

TY - JOUR

T1 - An oocyte donation protocol using the GnRH antagonist ganirelix acetate, does not compromise embryo quality and is associated with high pregnancy rates

AU - Vlahos, N. F.

AU - Bankowski, B. J.

AU - Zacur, Howard A

AU - Garcia, Jairo

AU - Wallach, Edward E

AU - Zhao, Y.

PY - 2005/6

Y1 - 2005/6

N2 - Purpose: To evaluate the effect of the GnRH antagonist, ganirelix acetate, on oocyte quality. Methods: Stimulation characteristics, implantation rates and clinical pregnancy rates were compared between 29 oocyte donors 21-31 years of age who underwent 31 cycles of ovarian stimulation with gonadotropins and ganirelix acetate, and 36 infertile couples of similar age range who underwent 51 cycles of ovarian stimulation using the same protocol. Results: A significantly lower number of embryos were transferred in the donor/recipient group as compared to the infertile group (2.32±0.54 vs. 2.82±0.71, P

AB - Purpose: To evaluate the effect of the GnRH antagonist, ganirelix acetate, on oocyte quality. Methods: Stimulation characteristics, implantation rates and clinical pregnancy rates were compared between 29 oocyte donors 21-31 years of age who underwent 31 cycles of ovarian stimulation with gonadotropins and ganirelix acetate, and 36 infertile couples of similar age range who underwent 51 cycles of ovarian stimulation using the same protocol. Results: A significantly lower number of embryos were transferred in the donor/recipient group as compared to the infertile group (2.32±0.54 vs. 2.82±0.71, P

KW - Ganirelix acetate

KW - GnRH antagonist

KW - IVF

KW - Oocyte donor

UR - http://www.scopus.com/inward/record.url?scp=21244446688&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=21244446688&partnerID=8YFLogxK

U2 - 10.1007/s00404-005-0726-2

DO - 10.1007/s00404-005-0726-2

M3 - Article

C2 - 15838696

AN - SCOPUS:21244446688

VL - 272

SP - 1

EP - 6

JO - Archives of Gynecology and Obstetrics

JF - Archives of Gynecology and Obstetrics

SN - 0932-0067

IS - 1

ER -