An objective evaluation of eyedrop instillation in patients with glaucoma

Jennifer L. Stone, Alan L. Robin, Gary D. Novack, David W. Covert, Gerald D. Cagle

Research output: Contribution to journalArticlepeer-review

131 Scopus citations


Objectives: To evaluate the performance of patients with ocular hypertension and glaucoma who are experienced in the instillation of topical ocular hypotensive medications. Methods: Weconducted a prospective, open-label study at a single private practice site. We enrolled 139 patients with a diagnosis of glaucoma or ocular hypertension who used 1 or more topical ocular hypotensive medications for at least 6 months and who instilled their own medications. Patients were questioned regarding their use of topical ocular hypotensive medications, and we used a video recording to evaluate patient performance of eyedrop instillation with 2 bottle designs. Results: Patients reported relatively good performance on eyedrop instillation. One hundred twenty-nine of 139 patients (92.8%) reported no problem putting in their eyedrops, and 86 of 139 (61.9%) believed that they never missed their eye when administering the drops. The proportions of patients who were able to instill a single drop into the eye without touching the bottle to the eye were 14 of 64 (21.9%) with a 15-mL bottle and 36 of 117 (30.8%) with a 2.5-mL bottle. Conclusions: Under a single direct observation, patients experienced in the use of topical ocular hypotensive agents performed relatively poorly when instilling a single eyedrop into the eye without touching the bottle tip to the eye or the ocular adnexae. Trial Registration: Identifier: NCT00522600.

Original languageEnglish (US)
Pages (from-to)732-736
Number of pages5
JournalArchives of ophthalmology
Issue number6
StatePublished - Jun 2009

ASJC Scopus subject areas

  • Ophthalmology


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