An investigation of semantic space in patients with schizophrenia

Mark S. Aloia, Monica L. Gourovitch, Daniel R. Weinberger, Terry E. Goldberg

Research output: Contribution to journalArticlepeer-review

Abstract

There has been increasing interest in the semantic cognitive system in schizophrenia. Recent findings suggest a possible breakdown of semantic information processing in this disorder. The current study attempts to further examine semantic organization in schizophrenia. Twenty-eight chronic, early-onset schizophrenic patients and 32 controls were matched for premorbid intelligence and compared in their ability to spontaneously cluster exemplars from a specific category during a fluency task. Using multidimensional scaling and clustering techniques, 11 exemplars occurring most frequently in both groups were chosen for examination of their relative "proximity" during word generation. Patients with schizophrenia showed a less stable two-dimensional organization of exemplars and were less likely to group exemplars into subordinate clusters than were normals. These results suggest that semantic networks are disorganized in these patients. These findings may have some implications for the debate over the origin of "thought disorder" in schizophrenia.

Original languageEnglish (US)
Pages (from-to)267-273
Number of pages7
JournalJournal of the International Neuropsychological Society
Volume2
Issue number4
DOIs
StatePublished - 1996
Externally publishedYes

Keywords

  • Language
  • Neuropsychology
  • Schizophrenia
  • Semantics

ASJC Scopus subject areas

  • Neuroscience(all)
  • Clinical Psychology
  • Clinical Neurology
  • Psychiatry and Mental health

Fingerprint Dive into the research topics of 'An investigation of semantic space in patients with schizophrenia'. Together they form a unique fingerprint.

Cite this