An introduction to pancreatic adenocarcinoma genetics, pathology and therapy

Scott E. Kern, Ralph H. Hruban, Manuel Hidalgo, Charles J. Yeo

Research output: Contribution to journalReview articlepeer-review

47 Scopus citations


Cancer is bad, but pancreatic cancer is especially so. Underlying the aggressive behavior of pancreatic cancer is a highly patterned set of biologic rules for its development. The accumulating discoveries regarding the genetic basis of pancreatic cancer and developments in the clinical management of the disease provide hope for meaningful improvements in the understanding and control of this disease.

Original languageEnglish (US)
Pages (from-to)607-613
Number of pages7
JournalCancer Biology and Therapy
Issue number6
StatePublished - 2002


  • BRCA2 mutations
  • Cancer precursors
  • Familial cancer
  • Genetic mutations
  • Mitomycin C
  • Pancreatic cancer
  • Pancreaticoduodenectomy
  • Telomeres

ASJC Scopus subject areas

  • Molecular Medicine
  • Oncology
  • Pharmacology
  • Cancer Research


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