An intrafascicular electrode with integrated amplifiers for peripheral nerve recording

Kian Ann Ng, Annarita Cutrone, Silvia Bossi, Sudip Nag, Ignacio Delgado-Martinez, Swathi Sheshadri, Claire A. Poulard, Yong Ping Xu, Shih Cheng Yen, Nitish V. Thakor

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

Thin-film longitudinal intrafascicular electrodes (tf-LIFE) are widely used for peripheral nerve recordings. tf-LIFEs are also promising electrodes for neural signal acquisition in future peripheral nerve prostheses. However, common mode signal interference, and electrical artifacts originating from long wire leads and wire movement are known problems encountered when using such electrodes, which lead to degradation in the recording quality. Here, we report an active tf-LIFE electrode implemented by integrating a neural amplifier chip die in close proximity to a tf-LIFE electrode. Consuming only 1mW and measuring 37 mm×7.2 mm×2.4 mm, this active tf-LIFE electrode creates a reliable connection and considerably shortens the distance between the electrode site and neural amplifier. This active electrode has demonstrated repeatable in-vivo recordings of compound action potentials from the rat sciatic nerve. Our results show that this electrode is suitable for repeated in-vivo recordings of compound action potentials from nerves in applications such as peripheral and visceral nerve interfaces that require low-noise stable nerve recordings.

Original languageEnglish (US)
Title of host publication2015 7th International IEEE/EMBS Conference on Neural Engineering, NER 2015
PublisherIEEE Computer Society
Pages394-397
Number of pages4
ISBN (Electronic)9781467363891
DOIs
StatePublished - Jul 1 2015
Externally publishedYes
Event7th International IEEE/EMBS Conference on Neural Engineering, NER 2015 - Montpellier, France
Duration: Apr 22 2015Apr 24 2015

Publication series

NameInternational IEEE/EMBS Conference on Neural Engineering, NER
Volume2015-July
ISSN (Print)1948-3546
ISSN (Electronic)1948-3554

Other

Other7th International IEEE/EMBS Conference on Neural Engineering, NER 2015
Country/TerritoryFrance
CityMontpellier
Period4/22/154/24/15

ASJC Scopus subject areas

  • Artificial Intelligence
  • Mechanical Engineering

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