An intractable case of prototheca keratitis and chronic endophthalmitis in stevens-johnson syndrome with boston type 1 keratoprosthesis

Jacqueline Ng; Don Minckler; Thomas J. Walsh; Marjan Farid

doi:10.1097/ICO.0000000000000949

An intractable case of prototheca keratitis and chronic endophthalmitis in stevens-johnson syndrome with boston type 1 keratoprosthesis

Jacqueline Ng, Don Minckler, Thomas J. Walsh, Marjan Farid

Research output: Contribution to journal › Article › peer-review

4 Scopus citations

Abstract

Purpose: To report a case of recalcitrant Prototheca spp. keratitis and endophthalmitis in a patient with Stevens-Johnson syndrome (SJS) and Boston type 1 keratoprosthesis (B1 KPro). Methods: Case report. Results: A 67-year-old female with a history of SJS with chronic severe ocular surface disease in her monocular left eye underwent placement of a B1 KPro. Her course was subsequently complicated by persistent Prototheca spp. keratitis and endophthalmitis requiring ongoing treatment with triazole and polyene antifungal agents and multiple surgical revisions of her keratoprosthesis. Conclusions: Protothecosis is an algal infection that is rarely pathologic in humans, but when present can be difficult to manage. We present the second known case of persistent chronic Prototheca spp. keratitis and endophthalmitis in a patient with long-standing SJS and B1 KPro.

Original language	English (US)
Pages (from-to)	1257-1260
Number of pages	4
Journal	Cornea
Volume	35
Issue number	9
DOIs	https://doi.org/10.1097/ICO.0000000000000949
State	Published - Jun 16 2016
Externally published	Yes

Keywords

Boston keratoprosthesis
endophthalmitis
keratitis
protothecosis
Stevens-Johnson syndrome

ASJC Scopus subject areas

General Medicine
Ophthalmology

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10.1097/ICO.0000000000000949

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title = "An intractable case of prototheca keratitis and chronic endophthalmitis in stevens-johnson syndrome with boston type 1 keratoprosthesis",

abstract = "Purpose: To report a case of recalcitrant Prototheca spp. keratitis and endophthalmitis in a patient with Stevens-Johnson syndrome (SJS) and Boston type 1 keratoprosthesis (B1 KPro). Methods: Case report. Results: A 67-year-old female with a history of SJS with chronic severe ocular surface disease in her monocular left eye underwent placement of a B1 KPro. Her course was subsequently complicated by persistent Prototheca spp. keratitis and endophthalmitis requiring ongoing treatment with triazole and polyene antifungal agents and multiple surgical revisions of her keratoprosthesis. Conclusions: Protothecosis is an algal infection that is rarely pathologic in humans, but when present can be difficult to manage. We present the second known case of persistent chronic Prototheca spp. keratitis and endophthalmitis in a patient with long-standing SJS and B1 KPro.",

keywords = "Boston keratoprosthesis, endophthalmitis, keratitis, protothecosis, Stevens-Johnson syndrome",

author = "Jacqueline Ng and Don Minckler and Walsh, {Thomas J.} and Marjan Farid",

year = "2016",

month = jun,

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doi = "10.1097/ICO.0000000000000949",

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AU - Ng, Jacqueline

AU - Minckler, Don

AU - Walsh, Thomas J.

AU - Farid, Marjan

PY - 2016/6/16

Y1 - 2016/6/16

N2 - Purpose: To report a case of recalcitrant Prototheca spp. keratitis and endophthalmitis in a patient with Stevens-Johnson syndrome (SJS) and Boston type 1 keratoprosthesis (B1 KPro). Methods: Case report. Results: A 67-year-old female with a history of SJS with chronic severe ocular surface disease in her monocular left eye underwent placement of a B1 KPro. Her course was subsequently complicated by persistent Prototheca spp. keratitis and endophthalmitis requiring ongoing treatment with triazole and polyene antifungal agents and multiple surgical revisions of her keratoprosthesis. Conclusions: Protothecosis is an algal infection that is rarely pathologic in humans, but when present can be difficult to manage. We present the second known case of persistent chronic Prototheca spp. keratitis and endophthalmitis in a patient with long-standing SJS and B1 KPro.

AB - Purpose: To report a case of recalcitrant Prototheca spp. keratitis and endophthalmitis in a patient with Stevens-Johnson syndrome (SJS) and Boston type 1 keratoprosthesis (B1 KPro). Methods: Case report. Results: A 67-year-old female with a history of SJS with chronic severe ocular surface disease in her monocular left eye underwent placement of a B1 KPro. Her course was subsequently complicated by persistent Prototheca spp. keratitis and endophthalmitis requiring ongoing treatment with triazole and polyene antifungal agents and multiple surgical revisions of her keratoprosthesis. Conclusions: Protothecosis is an algal infection that is rarely pathologic in humans, but when present can be difficult to manage. We present the second known case of persistent chronic Prototheca spp. keratitis and endophthalmitis in a patient with long-standing SJS and B1 KPro.

KW - Boston keratoprosthesis

KW - endophthalmitis

KW - keratitis

KW - protothecosis

KW - Stevens-Johnson syndrome

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An intractable case of prototheca keratitis and chronic endophthalmitis in stevens-johnson syndrome with boston type 1 keratoprosthesis

Abstract

Keywords

ASJC Scopus subject areas

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