TY - JOUR
T1 - An integrated automated analysis method for quantifying vessel stenosis and plaque burden from carotid MRI images
T2 - Combined postprocessing of MRA and vessel wall MR
AU - Adame, Isabel M.
AU - De Koning, Patrick J.H.
AU - Lelieveldt, Boudewijn P.F.
AU - Wasserman, Bruce A.
AU - Reiber, Johan H.C.
AU - Van Der Geest, Rob J.
N1 - Copyright:
Copyright 2008 Elsevier B.V., All rights reserved.
PY - 2006/8
Y1 - 2006/8
N2 - BACKGROUND AND PURPOSE - We report the evaluation of a semiautomated method for in vivo assessment of the severity of carotid atherosclerosis with minimal user interaction that combines 3-dimensional contrast-enhanced magnetic resonance angiography (CE-MRA) and vessel wall magnetic resonance imaging (MRI). METHODS - Lumen and outer-wall contours were automatically detected, and stenosis and plaque burden were estimated. The method was tested on 22 subjects (352 postcontrast, T1-weighted cross sections and 3-dimensional CE-MRA). RESULTS - We observed good correlation with expert contours: lumen and outer-wall area (r=0.96) and the degree of stenosis (r=0.97). CONCLUSIONS - The fusion of MRA and MRI reduces user interaction and improves contour detection, providing reproducible parameters to assess the severity of atherosclerosis.
AB - BACKGROUND AND PURPOSE - We report the evaluation of a semiautomated method for in vivo assessment of the severity of carotid atherosclerosis with minimal user interaction that combines 3-dimensional contrast-enhanced magnetic resonance angiography (CE-MRA) and vessel wall magnetic resonance imaging (MRI). METHODS - Lumen and outer-wall contours were automatically detected, and stenosis and plaque burden were estimated. The method was tested on 22 subjects (352 postcontrast, T1-weighted cross sections and 3-dimensional CE-MRA). RESULTS - We observed good correlation with expert contours: lumen and outer-wall area (r=0.96) and the degree of stenosis (r=0.97). CONCLUSIONS - The fusion of MRA and MRI reduces user interaction and improves contour detection, providing reproducible parameters to assess the severity of atherosclerosis.
KW - Atherosclerosis
KW - Carotid artery
KW - Magnetic resonance angiography
KW - Magnetic resonance imaging
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U2 - 10.1161/01.STR.0000231648.74198.f7
DO - 10.1161/01.STR.0000231648.74198.f7
M3 - Article
C2 - 16809565
AN - SCOPUS:33747151050
SN - 0039-2499
VL - 37
SP - 2162
EP - 2164
JO - Stroke
JF - Stroke
IS - 8
ER -