An examination of π-facial selectivity in the diels-alder reaction of a chiral diene - a synthesis of (+)-5,6,10-tri-(EPI)-Actinobolin.

Alan P. Kozikowski, Thaddeus R. Nieduzak, James P. Springer

Research output: Contribution to journalArticle

Abstract

The π-facial course of the Diels-Alder reaction of an L-threonine derived silyloxydiene has been examined during the course of a study aimed at the total synthesis of actinobolin/bactobolin.

Original languageEnglish (US)
Pages (from-to)819-822
Number of pages4
JournalTetrahedron Letters
Volume27
Issue number7
DOIs
StatePublished - 1986

ASJC Scopus subject areas

  • Biochemistry
  • Drug Discovery
  • Organic Chemistry

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