An evaluation of tween 80 effects on the survival and DNA repair in Escherichia coli following UV or gamma irradiation

Ruey K. Chi, J. J. Scocca, P C Huang

Research output: Contribution to journalArticle

Abstract

The notion that Tween 80 may be a DNA-repair inhibitor was tested with Escherichia coli. The results indicate that cell growth, colony-forming ability, and the rate and extent of removal of thymine-containing dimers from DNA are unchanged in the presence of Tween 80. We conclude that this detergent does not increase or diminish the effect of UV or gamma irradiation to bacteria.

Original languageEnglish (US)
Pages (from-to)1-8
Number of pages8
JournalMutation Research - Fundamental and Molecular Mechanisms of Mutagenesis
Volume49
Issue number1
DOIs
StatePublished - 1978

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Polysorbates
DNA Repair
Escherichia coli
Pyrimidine Dimers
Detergents
Bacteria
DNA
Growth

ASJC Scopus subject areas

  • Molecular Biology
  • Health, Toxicology and Mutagenesis
  • Medicine(all)

Cite this

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abstract = "The notion that Tween 80 may be a DNA-repair inhibitor was tested with Escherichia coli. The results indicate that cell growth, colony-forming ability, and the rate and extent of removal of thymine-containing dimers from DNA are unchanged in the presence of Tween 80. We conclude that this detergent does not increase or diminish the effect of UV or gamma irradiation to bacteria.",
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